ID A0A093CDZ2_9AVES Unreviewed; 671 AA.
AC A0A093CDZ2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Proprotein convertase subtilisin/kexin type 7 {ECO:0000313|EMBL:KFV11194.1};
DE Flags: Fragment;
GN ORFNames=N339_05951 {ECO:0000313|EMBL:KFV11194.1};
OS Pterocles gutturalis (yellow-throated sandgrouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Ciconiiformes; Pteroclidae; Pterocles.
OX NCBI_TaxID=240206 {ECO:0000313|EMBL:KFV11194.1, ECO:0000313|Proteomes:UP000053149};
RN [1] {ECO:0000313|EMBL:KFV11194.1, ECO:0000313|Proteomes:UP000053149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N339 {ECO:0000313|EMBL:KFV11194.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240}.
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DR EMBL; KL239666; KFV11194.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093CDZ2; -.
DR Proteomes; UP000053149; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd04059; Peptidases_S8_Protein_convertases_Kexins_Furin-like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.30.70.850; Peptidase S8, pro-domain; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR034182; Kexin/furin.
DR InterPro; IPR002884; P_dom.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR032815; S8_pro-domain.
DR InterPro; IPR038466; S8_pro-domain_sf.
DR PANTHER; PTHR42884; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED; 1.
DR PANTHER; PTHR42884:SF28; PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 7; 1.
DR Pfam; PF01483; P_proprotein; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR Pfam; PF16470; S8_pro-domain; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF54897; Protease propeptides/inhibitors; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51829; P_HOMO_B; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000053149};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}.
FT DOMAIN 412..549
FT /note="P/Homo B"
FT /evidence="ECO:0000259|PROSITE:PS51829"
FT REGION 115..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 107
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 148
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 326
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV11194.1"
FT NON_TER 671
FT /evidence="ECO:0000313|EMBL:KFV11194.1"
SQ SEQUENCE 671 AA; 74323 MW; 8971F25EB510E291 CRC64;
AGLVNMGRVG ELKGHYLFTY QPDGHAANEP EAIRRSVDTL FAQHDSVRWH SEQKLLKRSK
RSLHFNDPKY PQQWHLNNRK SPGKDINVTG VWERNVTGRG VTVVVVDDGV EHTIKDIQPN
YSPEGSYDLN SNDPDPMPHP DEENGNHHGT RCAGEIAAVP NNSFCTVGVA YGSRIAGIRV
LDGPLTDSME AIAFNKHYQI NDIYSCSWGP DDDGKTVDGP HQLGKAALQH GVIAGRRGFG
SIFVVASGNG GQHNDNCNYD GYANSIYTVT IGAVDETGSM PFYAEECASM LAVTFSGGDK
MMRSIVTTDW DLQKGTGCTE GHTGTSAAAP LAAGMIALML QVRPCLTWRD VQHIIVFPTT
KYEDRHAKWD VNQAGFSHSH QHGFGFPKAF GGGKAAHCPG LLSPFPWQVW ESVPYLASYV
SPVLKEGRSI PLLPQELEVA WNVTTTDLEL SGMRTLEHVA VTVTITHPRR GNLEIRLFCP
SGMMSLIGTT RSMDSDPNGF ADWTFSTVRC WGEEARGTYR LVVRDIGDES LRPGTLKQWQ
LTLYGSSWSP AEMKERQRLL EDAMSGRYLS SDFSLPCPPG LDIPEEQRYT ITANTLKTLL
LLGCFAVFWT FYYMLEVCLT RNNVGLDLTC NGSGTCRWYQ QGGKHRALES GLEMESVPLY
REKDIEDVEM E
//
