ID A0A093CIB6_TAUER Unreviewed; 1674 AA.
AC A0A093CIB6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Complement C5 {ECO:0000313|EMBL:KFV14213.1};
DE Flags: Fragment;
GN ORFNames=N340_01861 {ECO:0000313|EMBL:KFV14213.1};
OS Tauraco erythrolophus (Red-crested turaco).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Musophagiformes; Musophagidae; Tauraco.
OX NCBI_TaxID=121530 {ECO:0000313|EMBL:KFV14213.1, ECO:0000313|Proteomes:UP000053661};
RN [1] {ECO:0000313|EMBL:KFV14213.1, ECO:0000313|Proteomes:UP000053661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N340 {ECO:0000313|EMBL:KFV14213.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; KL462773; KFV14213.1; -; Genomic_DNA.
DR MEROPS; I39.952; -.
DR Proteomes; UP000053661; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00017; ANATO; 1.
DR CDD; cd02896; complement_C3_C4_C5; 1.
DR Gene3D; 1.50.10.20; -; 1.
DR Gene3D; 2.20.130.20; -; 1.
DR Gene3D; 2.40.50.120; -; 1.
DR Gene3D; 2.60.120.1540; -; 1.
DR Gene3D; 2.60.40.1930; -; 3.
DR Gene3D; 2.60.40.1940; -; 1.
DR Gene3D; 6.20.50.160; -; 1.
DR Gene3D; 2.60.40.690; Alpha-macroglobulin, receptor-binding domain; 1.
DR Gene3D; 1.20.91.20; Anaphylotoxins (complement system); 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR009048; A-macroglobulin_rcpt-bd.
DR InterPro; IPR036595; A-macroglobulin_rcpt-bd_sf.
DR InterPro; IPR011625; A2M_N_BRD.
DR InterPro; IPR011626; Alpha-macroglobulin_TED.
DR InterPro; IPR000020; Anaphylatoxin/fibulin.
DR InterPro; IPR018081; Anaphylatoxin_comp_syst.
DR InterPro; IPR041425; C3/4/5_MG1.
DR InterPro; IPR048843; C5_CUB.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR001599; Macroglobln_a2.
DR InterPro; IPR002890; MG2.
DR InterPro; IPR041555; MG3.
DR InterPro; IPR040839; MG4.
DR InterPro; IPR001134; Netrin_domain.
DR InterPro; IPR018933; Netrin_module_non-TIMP.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR InterPro; IPR008993; TIMP-like_OB-fold.
DR PANTHER; PTHR11412:SF83; COMPLEMENT C5; 1.
DR PANTHER; PTHR11412; MACROGLOBULIN / COMPLEMENT; 1.
DR Pfam; PF00207; A2M; 1.
DR Pfam; PF07703; A2M_BRD; 1.
DR Pfam; PF07677; A2M_recep; 1.
DR Pfam; PF01821; ANATO; 1.
DR Pfam; PF21309; C5_CUB; 1.
DR Pfam; PF17790; MG1; 1.
DR Pfam; PF01835; MG2; 1.
DR Pfam; PF17791; MG3; 1.
DR Pfam; PF17789; MG4; 1.
DR Pfam; PF01759; NTR; 1.
DR Pfam; PF07678; TED_complement; 1.
DR SMART; SM01360; A2M; 1.
DR SMART; SM01359; A2M_N_2; 1.
DR SMART; SM01361; A2M_recep; 1.
DR SMART; SM00104; ANATO; 1.
DR SMART; SM00643; C345C; 1.
DR SUPFAM; SSF49410; Alpha-macroglobulin receptor domain; 1.
DR SUPFAM; SSF47686; Anaphylotoxins (complement system); 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 1.
DR SUPFAM; SSF50242; TIMP-like; 1.
DR PROSITE; PS01177; ANAPHYLATOXIN_1; 1.
DR PROSITE; PS01178; ANAPHYLATOXIN_2; 1.
DR PROSITE; PS50189; NTR; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000053661};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 692..727
FT /note="Anaphylatoxin-like"
FT /evidence="ECO:0000259|PROSITE:PS01178"
FT DOMAIN 1530..1674
FT /note="NTR"
FT /evidence="ECO:0000259|PROSITE:PS50189"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV14213.1"
FT NON_TER 1674
FT /evidence="ECO:0000313|EMBL:KFV14213.1"
SQ SEQUENCE 1674 AA; 187761 MW; 8516414981450C0B CRC64;
LLFSGTTFSQ EKTYVLTAPK IFRVGASQKV VVQAFGYEKE FAVNIAIRSF PDKLAVFSSG
HISLTPANKF QDAVTLTLQP TDLPRTEISV KYVYLEAVSP HFTRVKKIPI SYENGFLFIH
TDKPIYTPDQ SVKVRVYSLN EELQPARRET VLTFVDPEGV KVDIIEEEDF TGIVSFPDFK
IPPNPKYGIW KIEAKYKKNF ETSAVAKFEV KEYAMPSFSI VIEPESNFIS SDKFENFRIA
VKASYFYNKR LASADVFLRF GIIEETEKRM MPHAMHLTRI ENGVAEINFN SKQAVNFIGF
QSLEELDGSY LYIVASVLES SGGLSAEAEF SGVKFAVSPY KLSLIATPLF VKPGLPFFIK
VQVKDTVDHF VGNIPITITA KSFSEQMGET ELISEGSESG RRKTSVNDGT ALFVVNVPSD
SKMLEFQIKT ADPHLSDENQ ASKTYEAKAY SSLSQSYLYI NWASNHKILK VGDFININVY
PHSQYIHKIH HYSYLIVSRG KIVSFGTQKR VKDLEYEHLT FQITQEMVPS ARLIVYYIVM
GEETAELVAD SVWLNVEQKC GNSLDIKLQS SKEILNPAEV VSLNMKTQFN SFVALSSIDK
AVYGVTGRGK RALEKVMLHL EKSDLGCGAG GGRNNVDVFR MAGLTFLTNA NADDSNEAGE
TCNEVLRTKR SDFKERILKE ASKYVHPEIR KCCMAGVKAY PVTETCSDRA QRIRSSERCI
SAFRNCCEFA NRLREEEPNK LLILARMHFE AGLELGEAEV RSYFPESWLW EVHQVTPRSK
TLSVTLPDSL TTWEVQGVGI SDKGICVVAP LEVPVVKDIF LSVYVPYSVV RGEQIELKGS
VYNHRASPIK FCVKIAAGNG ICSFGDSSPT GSRLRNCNVK NLDGGSSSPV TFRILPLELG
LHTINFTLLT AGNSETVVKT LRVMPEGVKK ELHAGFTLDP QGVYGSIKRR QEFRYKIPLN
LVPKTKIDRS VSVKGHLMGE AIAAIVSPSG ISILTNLPKG SAEAELMSIA PVFYVFHYLE
ESDNWHLLGP ETLTSRTQMR RKMKEGIVSI LSFRNSDFSY SMWKNGQAST WLTAFALRIL
GQVNQYINLD QISICNSLLW LIDNCQMPDG SFSEFSNYQP VKLQGTLPRE AKEKSLYLTA
FSIIGIEKSI KICPTQKIHD AKNKAGDYLM KNVQSAQSPF TMAITSYALA LVDLNHHSAR
SAFSALKKEA YVIGDPPIYR FWKDTFKTVD QHTPSSVTAQ MVETTAYALL TTLLRGDKNY
ANPIIKWLSE EQRHGGGFYS TQDTINALEA LAEYSLLVKR LNLDMNVKVT YKNYGDLNLF
KLTEDNFVGR TMTVPLDDDI YVSTGSSTGI ATVNVKTVYN TIGTSEESCN FELKIVPKRD
DGYRREDGEP LGRLEACAKY RPGLREPQSG SAHAVMDIGL VSGLEANTED LSTLASGVDQ
LIADYEIKDG HVVLQIDSVC YPFHNSNNFL CVEFRISELF QVGMLNPATF TVYEYHAPDK
RCSIFYNPYG NEKLVRLCEG DECKCMEAEC GRVQERLDRS ITADTRREAA CQNDIAYVYK
VNILSRSEEG SFVKYSATLL DLYKRGQAFA QKNDEITFVK KKTCTDVELS PGEQYLIMGK
EALKITVGYN FKFQYPLDSS TWIEWWPSNT ACTFCQEFLN TMEDFAEDLI ISGC
//
