ID A0A093CRC8_TAUER Unreviewed; 748 AA.
AC A0A093CRC8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Serine/threonine-protein kinase N2 {ECO:0000313|EMBL:KFV18435.1};
DE Flags: Fragment;
GN ORFNames=N340_02076 {ECO:0000313|EMBL:KFV18435.1};
OS Tauraco erythrolophus (Red-crested turaco).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Musophagiformes; Musophagidae; Tauraco.
OX NCBI_TaxID=121530 {ECO:0000313|EMBL:KFV18435.1, ECO:0000313|Proteomes:UP000053661};
RN [1] {ECO:0000313|EMBL:KFV18435.1, ECO:0000313|Proteomes:UP000053661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N340 {ECO:0000313|EMBL:KFV18435.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.13;
CC Evidence={ECO:0000256|ARBA:ARBA00000946};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.13; Evidence={ECO:0000256|ARBA:ARBA00000569};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; KL469840; KFV18435.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093CRC8; -.
DR Proteomes; UP000053661; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004697; F:diacylglycerol-dependent serine/threonine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd11637; HR1_PKN3_3; 1.
DR Gene3D; 1.10.287.160; HR1 repeat; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011072; HR1_rho-bd.
DR InterPro; IPR036274; HR1_rpt_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR24356; SERINE/THREONINE-PROTEIN KINASE; 1.
DR PANTHER; PTHR24356:SF318; SERINE_THREONINE-PROTEIN KINASE N3; 1.
DR Pfam; PF02185; HR1; 2.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00742; Hr1; 2.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF46585; HR1 repeat; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
DR PROSITE; PS51860; REM_1; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01207};
KW Kinase {ECO:0000313|EMBL:KFV18435.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000053661};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000313|EMBL:KFV18435.1}.
FT DOMAIN 1..65
FT /note="REM-1"
FT /evidence="ECO:0000259|PROSITE:PS51860"
FT DOMAIN 73..152
FT /note="REM-1"
FT /evidence="ECO:0000259|PROSITE:PS51860"
FT DOMAIN 173..336
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 514..748
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 543
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV18435.1"
FT NON_TER 748
FT /evidence="ECO:0000313|EMBL:KFV18435.1"
SQ SEQUENCE 748 AA; 84250 MW; 1A8B5A5E3E7509C3 CRC64;
KVEALKKQLH VEMKVKQGAE NMIQMYSTSK ERKLLATAQQ MLQDSKTKIE IIRMHIVKVS
QSAGGMEDTV DPAVRMGTAI SALELRIEEL RHHLRIEAAV AEGAKNVLKI LGGSRVQDRK
FLAEAQGRLQ ESSQKIDLLR LSLERQLSEL SPEHPKRALI KQELVNTSSL GAQHGNIQPT
SVIKPTALTG TLEVRLMGCQ DLLENVPGRS RMASSSPVCG SPSDLRSLSR PRVGLGIHGR
SVAGKYLRNE EPCNEVLAVL KVDNKVVGQT NWGPVNNQAW DQSFVIELDR SRELEIAIYW
RDWRELCAVK FLRLDDFLDN ERHGMCLSLE PQGMLFAEVM FCNPVIERKP KLQRQRRIFP
KQKGKEFLRA PQMNINVAAW GRLMMSFLPP CSSLSTLSPP LHDPIHTAFS PVPPQSHVDS
MSKLSSGFPV AKLTFADEAP PKPPRLASLG EPELVLLLPV EMKVRLLPLG AVSSPVRVRK
VRVTHSFLQW QNSSIKPNSS GFQPRKRTVH LEDFHCIAML GRGHFGKVLL AQYKPTGKLY
AIKALKKKDI IRRDEIDSLN CEKRIFEVVN SSDHPFLVNM FACFQTPHHA CFVMEYTPGG
DLMMRIHEDV FPEHMAQFYT ACVVLGLQFL HEKKIIYRDL KLDNLLLDAE GFVKIADFGL
CKEGIGFGDR TNTFCGTPEF LAPEVLTDIS YTRAVDWWGL GVLIYEMLVG ESPFPGDDEE
EVFDSIVNDE VRYPRFLSSE ALSIIRKV
//
