ID A0A093D7B7_TAUER Unreviewed; 523 AA.
AC A0A093D7B7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Polycystic kidney disease 2-like 2 protein {ECO:0000313|EMBL:KFV20477.1};
DE Flags: Fragment;
GN ORFNames=N340_04576 {ECO:0000313|EMBL:KFV20477.1};
OS Tauraco erythrolophus (Red-crested turaco).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Musophagiformes; Musophagidae; Tauraco.
OX NCBI_TaxID=121530 {ECO:0000313|EMBL:KFV20477.1, ECO:0000313|Proteomes:UP000053661};
RN [1] {ECO:0000313|EMBL:KFV20477.1, ECO:0000313|Proteomes:UP000053661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N340 {ECO:0000313|EMBL:KFV20477.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the polycystin family.
CC {ECO:0000256|ARBA:ARBA00007200}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KL475569; KFV20477.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093D7B7; -.
DR Proteomes; UP000053661; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR013122; PKD1_2_channel.
DR InterPro; IPR003915; PKD_2.
DR InterPro; IPR046791; Polycystin_dom.
DR PANTHER; PTHR10877:SF47; POLYCYSTIC KIDNEY DISEASE 2-LIKE 2 PROTEIN; 1.
DR PANTHER; PTHR10877; POLYCYSTIN FAMILY MEMBER; 1.
DR Pfam; PF08016; PKD_channel; 1.
DR Pfam; PF20519; Polycystin_dom; 1.
DR PRINTS; PR01433; POLYCYSTIN2.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053661};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 13..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 387..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 449..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 57..252
FT /note="Polycystin"
FT /evidence="ECO:0000259|Pfam:PF20519"
FT DOMAIN 253..477
FT /note="Polycystin cation channel PKD1/PKD2"
FT /evidence="ECO:0000259|Pfam:PF08016"
FT DISULFID 121..134
FT /evidence="ECO:0000256|PIRSR:PIRSR603915-2"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV20477.1"
FT NON_TER 523
FT /evidence="ECO:0000313|EMBL:KFV20477.1"
SQ SEQUENCE 523 AA; 61288 MW; 737031FBF6DAF6E0 CRC64;
SRELELKSTL RELVIYIVFL TDLCILAFSM VSTDMYYLNE VMSRVFLEPS SEDDGSGFRS
IRSRADFWRF AEGPLLDGLY WEKWYNNKTS TLQNNNSHIY YENLLLGVAQ IRQLKVRNNT
CSVHPYFHAV LEGCYSEYHY RAEDRSDFGL RNESEWKYTS ASSLSPWYWG SMGLYSSGGF
MFTLPKSKQE SVEKLVFLRQ NSWLTRGTRA VFIDFSTYNA NINLFCIIRL VVEFPATGGA
LTSSQICSVK LLRYITYYDY FLAFCEITFC LFIITFIIQE TLQIAKLKKE YFRRAWNWLD
LLLLVVSILA IAFNIYRTVK VSLLMEKLLS DAHVYPDFYF LAFWQVLYNN MIAVNIFFAW
IKIFKYIRFN KTMAQLSSTL SRCAKDIIGF AVMFFIVFFA YAQLGYLVFG SQVEEFSTFQ
NCIFTQFRIV LGDFNFESLE AADRILGPIY FITFVFFVFF VLLNMFLAII NDTYSEVKAD
FEVIPSQELQ IRNLFRQSCN KALVKLKLKK PETDTNPEDE NLE
//
