ID A0A093E7L1_TAUER Unreviewed; 816 AA.
AC A0A093E7L1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=receptor protein-tyrosine kinase {ECO:0000256|ARBA:ARBA00011902};
DE EC=2.7.10.1 {ECO:0000256|ARBA:ARBA00011902};
DE Flags: Fragment;
GN ORFNames=N340_00938 {ECO:0000313|EMBL:KFV10466.1};
OS Tauraco erythrolophus (Red-crested turaco).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Musophagiformes; Musophagidae; Tauraco.
OX NCBI_TaxID=121530 {ECO:0000313|EMBL:KFV10466.1, ECO:0000313|Proteomes:UP000053661};
RN [1] {ECO:0000313|EMBL:KFV10466.1, ECO:0000313|Proteomes:UP000053661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N340 {ECO:0000313|EMBL:KFV10466.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-
CC [protein]; Xref=Rhea:RHEA:10596, Rhea:RHEA-COMP:10136, Rhea:RHEA-
CC COMP:10137, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:46858,
CC ChEBI:CHEBI:82620, ChEBI:CHEBI:456216; EC=2.7.10.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001171};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; KL457768; KFV10466.1; -; Genomic_DNA.
DR RefSeq; XP_009977559.1; XM_009979257.1.
DR AlphaFoldDB; A0A093E7L1; -.
DR GeneID; 104373369; -.
DR KEGG; teo:104373369; -.
DR CTD; 4233; -.
DR OrthoDB; 1614410at2759; -.
DR Proteomes; UP000053661; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd00603; IPT_PCSR; 1.
DR CDD; cd01180; IPT_plexin_repeat1; 1.
DR CDD; cd01179; IPT_plexin_repeat2; 1.
DR CDD; cd05058; PTKc_Met_Ron; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008266; Tyr_kinase_AS.
DR InterPro; IPR020635; Tyr_kinase_cat_dom.
DR PANTHER; PTHR24416:SF483; HEPATOCYTE GROWTH FACTOR RECEPTOR; 1.
DR PANTHER; PTHR24416; TYROSINE-PROTEIN KINASE RECEPTOR; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR Pfam; PF01833; TIG; 3.
DR PRINTS; PR00109; TYRKINASE.
DR SMART; SM00429; IPT; 4.
DR SMART; SM00219; TyrKc; 1.
DR SUPFAM; SSF81296; E set domains; 3.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Kinase {ECO:0000256|ARBA:ARBA00023137};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:KFV10466.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053661};
KW Transferase {ECO:0000256|ARBA:ARBA00023137};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Tyrosine-protein kinase {ECO:0000256|ARBA:ARBA00023137}.
FT TRANSMEM 366..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 513..780
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 545
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV10466.1"
FT NON_TER 816
FT /evidence="ECO:0000313|EMBL:KFV10466.1"
SQ SEQUENCE 816 AA; 90758 MW; CDF9E64ACD75BA9C CRC64;
QILPSSAPLE GGTKLTLCGW DFGFSKNNRF ELKNTVVHIG GQICALEAKS SNQNKLECTV
PAAKYPSFNI SSSVSVGHGK TLFNTFSYVN PVITSISPTY GPKSGGTLLT VAGKYLNSGK
SRRIFVGEKP CTLKSISGST VECYTPAQRI PQEYRVRVAI DEAVRDASGH FTYREDPVVL
KIHPAKSFLS GGSTITAQGI NLNSVCFPQM VITVPKLGMN FSVACSHRSS SEIICCTTPS
LKAFNLQPPF VTKVFFIFDG VSSLYFDFDY VNNPVFKHFE KPVLISRGNQ NILEIKGNYI
DSEAVKGEVL KVGNKSCENL LLQSESILCT VPSDLLKSNS ELNIEWKQEV LSTVIGKVLI
RQDQNFTGLI AGLVSTSVLI FIFLVFFFWR RKKKQIKDLG SDLVRYDGRV HTPHLDRLVS
ARSVSPTTEM VSSESVDYRS TFLDDQFPSM SQNGSCRPAQ YPHSDLSPIL SSGDSDLASP
LLQTNVHIDI SALNPDLVKE VQHVVIGADS LIVHFSEVIG RGHFGCVYHG TLLDNDGRKI
HCAVKSLNRI TDLEEVAQFL KEGIIMKDFT HPNVLSLLGI CLPNEGSPLV VLPYMKHGDL
RNFIRNETHN PTVKDLIGFG LQVAKGMKYL ASKKFVHRDL AARNCMLDEK FTVKVADFGL
ARDVYDKEYY SVHNKTGAKL PVKWMALESL QTQKFTTKSD VWSFGVLLWE LMTRGAPPYP
DVNSFDITVY LLQGRRLLQP EYCPDPLYEV MLKCWHPKPE MRPAFSELVS KISTIFSTFI
GEHYVHVNAT YVNVKCIAPY PSLLSSQDNT DMDVDT
//
