ID A0A093F7T9_GAVST Unreviewed; 668 AA.
AC A0A093F7T9;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Histone-lysine N-methyltransferase NSD3 {ECO:0000313|EMBL:KFV50291.1};
DE Flags: Fragment;
GN ORFNames=N328_00639 {ECO:0000313|EMBL:KFV50291.1};
OS Gavia stellata (Red-throated diver) (Colymbus stellatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gaviiformes; Gaviidae; Gavia.
OX NCBI_TaxID=37040 {ECO:0000313|EMBL:KFV50291.1, ECO:0000313|Proteomes:UP000054313};
RN [1] {ECO:0000313|EMBL:KFV50291.1, ECO:0000313|Proteomes:UP000054313}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N328 {ECO:0000313|EMBL:KFV50291.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KK619199; KFV50291.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093F7T9; -.
DR Proteomes; UP000054313; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0042054; F:histone methyltransferase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd15658; PHD4_NSD3; 1.
DR CDD; cd15661; PHD5_NSD3; 1.
DR CDD; cd20166; PWWP_NSD3_rpt2; 1.
DR CDD; cd19212; SET_NSD3; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 4.
DR InterPro; IPR006560; AWS_dom.
DR InterPro; IPR041306; C5HCH.
DR InterPro; IPR047458; PHD4_NSD3.
DR InterPro; IPR047527; PHD5_NSD3.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR047453; PWWP_NSD3_rpt2.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR047461; SET_NSD3.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22884:SF473; HISTONE-LYSINE N-METHYLTRANSFERASE NSD3; 1.
DR PANTHER; PTHR22884; SET DOMAIN PROTEINS; 1.
DR Pfam; PF17907; AWS; 1.
DR Pfam; PF17982; C5HCH; 1.
DR Pfam; PF00855; PWWP; 1.
DR Pfam; PF00856; SET; 1.
DR SMART; SM00570; AWS; 1.
DR SMART; SM00249; PHD; 5.
DR SMART; SM00508; PostSET; 1.
DR SMART; SM00293; PWWP; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 3.
DR SUPFAM; SSF82199; SET domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS51215; AWS; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000313|EMBL:KFV50291.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054313};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KFV50291.1};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 158..202
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 207..281
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT DOMAIN 352..402
FT /note="AWS"
FT /evidence="ECO:0000259|PROSITE:PS51215"
FT DOMAIN 404..521
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 528..544
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT COILED 293..320
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 554..581
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV50291.1"
FT NON_TER 668
FT /evidence="ECO:0000313|EMBL:KFV50291.1"
SQ SEQUENCE 668 AA; 75675 MW; 078799E896BE13FE CRC64;
KICESSGESL LSCEGECCSV FHMECLGLKS MPDEKFICTE CKNGEHTCFS CKLPGKDVKR
CSVNTCGKFY HEACVRKFAT ALFESRGFRC PQHCCTACSV DKDIHKASKG RMVRCFRCPI
AYHSGDGCIA AGSLFVSSHI LICSNHSKRN HSSSAVNVGF CFVCARGGKL LCCESCPASF
HPECLNIEMP EGCWNCNDCK AGKKLRYKQI VWVKLGNYRQ VCYFWVLMLW MWWPAEICNP
RSVPLNIQGL KHDIGDFPVF FFGSHDYYWV HQGRVFPYVE GDKSFAEGQT SINKTFKKAL
EEAAKRFQEL KAQRESKEAL EIERNSRKPP PYKHIKSNKV IGKVQIQVAD LSEIPRCNCK
PSDENPCGLE SECLNRMLQY ECHPQVCPAG ERCQNQCFTK RLYPDAEIIK TDRRGWGLRT
KRSIKKGEFV NEYVGELIDE EECRLRIKRA HENSVTNFYM LTVTKDRIID AGPKGNYSRF
MNHSCNPNCE TQKWTVNGDI RVGLFALCDI PAGMELTFNY NLDCLGNGRT ECHCGAENCS
GFLGVRPKTA FATANEEKVK NAKLKQKKRK IKTEQKQMHE DNCFQCGDGG ELVMCDKKDC
PKAYHLLCLN LTQPPFGKWE CPWHQCDICS NPAVSFCEFC PHSFCKDHEK GALVASALDG
RLCCSAHD
//
