ID   A0A093H133_GAVST        Unreviewed;       417 AA.
AC   A0A093H133;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Neuroepithelial cell-transforming 1 {ECO:0000313|EMBL:KFV48453.1};
DE   Flags: Fragment;
GN   ORFNames=N328_07343 {ECO:0000313|EMBL:KFV48453.1};
OS   Gavia stellata (Red-throated diver) (Colymbus stellatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Gaviiformes; Gaviidae; Gavia.
OX   NCBI_TaxID=37040 {ECO:0000313|EMBL:KFV48453.1, ECO:0000313|Proteomes:UP000054313};
RN   [1] {ECO:0000313|EMBL:KFV48453.1, ECO:0000313|Proteomes:UP000054313}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N328 {ECO:0000313|EMBL:KFV48453.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   EMBL; KK615546; KFV48453.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093H133; -.
DR   Proteomes; UP000054313; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd13224; PH_Net1; 1.
DR   CDD; cd00160; RhoGEF; 1.
DR   Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR035899; DBL_dom_sf.
DR   InterPro; IPR000219; DH-domain.
DR   InterPro; IPR001331; GDS_CDC24_CS.
DR   InterPro; IPR037853; Net1_PH.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR46006:SF4; NEUROEPITHELIAL CELL-TRANSFORMING GENE 1 PROTEIN; 1.
DR   PANTHER; PTHR46006; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF00621; RhoGEF; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00325; RhoGEF; 1.
DR   SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS00741; DH_1; 1.
DR   PROSITE; PS50010; DH_2; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054313}.
FT   DOMAIN          92..274
FT                   /note="DH"
FT                   /evidence="ECO:0000259|PROSITE:PS50010"
FT   DOMAIN          304..417
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFV48453.1"
FT   NON_TER         417
FT                   /evidence="ECO:0000313|EMBL:KFV48453.1"
SQ   SEQUENCE   417 AA;  47810 MW;  13078A68E2116489 CRC64;
     QEPSNKRVRP LARVTSLANL ISPVRNGAVR RFGQTIQVKS RAFYDSKSPG CAQKSCSSRS
     AAPTPPKRRN SVLWSEMLDV SMKESLSTKE IKRQEAIYEM SRGEQDLIED LKLARKAYHD
     PMLKLSIMSE EELTHIFGDL DSYIPLHEDL LASLGEATKP DGTVEQIGPI LVKWLPRLHA
     YKGYCSNQLA AKALLDQKKQ DRRVQDFLQR CLESPFSRKL DLWSFLDIPR SRLVKYPLLL
     KEILRHTPKD HPDIQILEEA ISIIQGVLSD INLKKGESEC QYYIDKLEYL DEKQKDPRIE
     GSKALLCHGE LKNKNGHKLY VFLFQDILVL TRPVTRNERQ AYQVYRQPIP VQELLLEDLQ
     DGDVKMGGSF RGAFGNSDKA KNIFRVRFQD PSPGQSHTLQ ANDVFHKQQW VNCIRTA
//