ID A0A093HHK3_STRCA Unreviewed; 616 AA.
AC A0A093HHK3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 03-MAY-2023, entry version 36.
DE SubName: Full=Kelch-like 8 {ECO:0000313|EMBL:KFV82128.1};
GN ORFNames=N308_05681 {ECO:0000313|EMBL:KFV82128.1};
OS Struthio camelus australis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae;
OC Struthio.
OX NCBI_TaxID=441894 {ECO:0000313|EMBL:KFV82128.1, ECO:0000313|Proteomes:UP000053584};
RN [1] {ECO:0000313|EMBL:KFV82128.1, ECO:0000313|Proteomes:UP000053584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N308 {ECO:0000313|EMBL:KFV82128.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL206412; KFV82128.1; -; Genomic_DNA.
DR RefSeq; XP_009674820.1; XM_009676525.1.
DR RefSeq; XP_009674821.1; XM_009676526.1.
DR AlphaFoldDB; A0A093HHK3; -.
DR STRING; 441894.ENSSCUP00000009808; -.
DR Ensembl; ENSSCUT00000012713; ENSSCUP00000009808; ENSSCUG00000007076.
DR GeneID; 104145152; -.
DR KEGG; scam:104145152; -.
DR CTD; 57563; -.
DR OrthoDB; 5472491at2759; -.
DR Proteomes; UP000053584; Unassembled WGS sequence.
DR GO; GO:0031463; C:Cul3-RING ubiquitin ligase complex; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0016567; P:protein ubiquitination; IEA:Ensembl.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR CDD; cd18448; BACK_KLHL8; 1.
DR CDD; cd18238; BTB_POZ_KLHL8; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR PANTHER; PTHR24412:SF480; KELCH-LIKE PROTEIN 8; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 6.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 3.
DR PRINTS; PR00501; KELCHREPEAT.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 2.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000053584};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 63..130
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 616 AA; 68116 MW; A4C4F68F77DECFFE CRC64;
MASESMVPEQ AKQHLIKGKR QQQQQTRSSN SDGEDEIFVF EANEAWKDFH SSLLHFFEAG
ELCDITLKVG SKLISCHKLV LACVIPYFRA MFLSEMAEAK QTLIEIRDFD GDAIEDLVKF
AYSSRLTLTV DNVQPLLYAA CILQVELVAK ACCEYMKLHF HPSNCLAVRA FAESHNRIDL
MDMADQYACE HFAEVVDCED FVSVSPQHLH KLLSSSDLNI ENEKQVYNAA IKWLLANPQH
HAMWLDEILA QVRLPLLPIC FLMGVVAKEE IVKQNLKCRD LLDEARNYHL HLSSRAVPDF
EYSIRTTPRK QTAGVLFCVG GRGGSGDPFR SIECYSISKN NWFFGPEMNS RRRHVGVISV
GGKVYAVGGH DGNEHLGSME VFDPLTNKWM MKASMNTKRR GIALASLGGP IYAIGGLDDN
TCFSDVERYD IESDRWSGIA PMNTPRGGVG SVALVNHVYA VGGNDGVASL SSVEKYDPHL
DKWIEVKEMG QRRAGNGVSE LHGCLYVVGG FDDNSPLSSV ERFDPRSNKW EYVAELTTPR
GGVGIATLMG KIFAVGGHNG NAYLNTVEAF DPIVNRWELV GSVSHCRAGA GVAVCSCLSS
QIRDVGQGSS NVVDCM
//
