ID   A0A093HSH3_STRCA        Unreviewed;      1170 AA.
AC   A0A093HSH3;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=Tectonin beta-propeller repeat-containing protein 1 {ECO:0000256|ARBA:ARBA00016409};
DE   Flags: Fragment;
GN   ORFNames=N308_08843 {ECO:0000313|EMBL:KFV85643.1};
OS   Struthio camelus australis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae;
OC   Struthio.
OX   NCBI_TaxID=441894 {ECO:0000313|EMBL:KFV85643.1, ECO:0000313|Proteomes:UP000053584};
RN   [1] {ECO:0000313|EMBL:KFV85643.1, ECO:0000313|Proteomes:UP000053584}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N308 {ECO:0000313|EMBL:KFV85643.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, autophagosome membrane
CC       {ECO:0000256|ARBA:ARBA00004652}. Lysosome membrane
CC       {ECO:0000256|ARBA:ARBA00004656}.
CC   -!- SIMILARITY: Belongs to the TECPR1 family.
CC       {ECO:0000256|ARBA:ARBA00005966}.
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DR   EMBL; KL206788; KFV85643.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093HSH3; -.
DR   STRING; 441894.ENSSCUP00000020713; -.
DR   Proteomes; UP000053584; Unassembled WGS sequence.
DR   GO; GO:0000421; C:autophagosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR   CDD; cd13300; PH1_TECPR1; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR006624; Beta-propeller_rpt_TECPR.
DR   InterPro; IPR010482; Peroxin.
DR   InterPro; IPR006614; Peroxin/Ferlin.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR23250; DYSFERLIN-RELATED; 1.
DR   PANTHER; PTHR23250:SF1; TECTONIN BETA-PROPELLER REPEAT-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF06462; Hyd_WA; 2.
DR   Pfam; PF06398; Pex24p; 2.
DR   Pfam; PF19193; Tectonin; 2.
DR   SMART; SM00694; DysFC; 2.
DR   SMART; SM00693; DysFN; 2.
DR   SMART; SM00706; TECPR; 11.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   3: Inferred from homology;
KW   Lysosome {ECO:0000256|ARBA:ARBA00023228};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053584};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          621..730
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          466..496
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1151..1170
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1170
FT                   /evidence="ECO:0000313|EMBL:KFV85643.1"
SQ   SEQUENCE   1170 AA;  131732 MW;  56B928409D9684AC CRC64;
     MSNSLLWAVD IFGRVYTLST VGQYWELCKD TQLEFKRVSA IKQCCWGIAC DHQVYTYVFS
     GDVPIRYQEE TYENQRWNPI GGFCEKLMPS DRWQWSDVSG LKHQQLDSFT LPSPHWEWES
     DWYVDENIGG EPTEKGGWTY AIDFPSTYTK DKKWNSCVRR RRWIRYRRYK SRDVWAKIIS
     HDDPDQLPDP FNDISIGGWE ITDEPVGRLS VWAVSLQGRV WYRENVCHHN PEGSVWSLIA
     TPGEVVQISC GPYDLLWATL WEGQAIVREG IDRNNPQGIS WSIVESPSSE NGIMHISVGV
     DVVWGVTKDR KVWFRRGVNS HNPCGTSWIE MVGEMMMVNV GLNNQVWGIG CDDRAIYFRQ
     GVTPSELSGK TWKAIVSGRE SDRSQTGSST SLLSAGCFFT DDIQNQTNAI IQGDADTSSD
     SELPSVSVNL ANNTPVLGAA ASNSGNGAGH QTAEISANLA VDPLDSDQGE ASVASTSNEK
     ASLEKHKSST NQNPSAELQW TNIDLKEAQK HPVLSGSTFA ETSSLSSLGM FSVGAEEQYG
     ADEHPLWAWV SGGGCHVDSH SPLKWFTVPS GLTSSVQSLS LSITPAQTAA WRKQIFQQLS
     ERTKRELENF RHYEQAIEQS VWVKTGTLQW WRNWKPQKWM DVRVALEQFT GSDGMRDSIL
     FIYYMYHEEK KYIHVFLNEV TILVEVLNEA KHSFALYTPE RTKQRWPIRL AATTEQEMHD
     WLALLSMSCC ESRRIQGPPS HQAIWSVTCK GDIFVSEPSP ELEAGPHLMP CDQMFWRQIG
     GHLRLIECNN RGIVWGIGYD HTAWVYTGGY GGGFIQGLAS SADNIYTQSD VKCVYIYENQ
     RWNPVTGYSS RGLPTDRHMW SDASGLQECT KMNTKPPSPQ WSWVSDWYID FNTSGGTDRE
     GWQYAADFPA SYHGHKTMKD FVRRRRWARK CKIVTNGPWL EVPPVTLWDI SIIPSSDADD
     EESVALWAIS DKGDVLCRLG VTQQNPAGTS WLHVGTDQPF ISVSIGAFYQ VWAIARDGSA
     FYRGSVAPKK PAGDCWYHIP SPQKQKLKQV SVGRTSVFVL DKNGNLWYRQ GITPSYPQGS
     TWDHVSNNIR KMSVGPLDQV WVIADKVQGS HSLSCGTVCH RTGVQPMEPK GLAWDYGIGG
     GWEHITVRGN ATEASRVNTH DTSEEDPARS
//