ID A0A093IEX3_EURHL Unreviewed; 672 AA.
AC A0A093IEX3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=mRNA export factor GLE1 {ECO:0000256|ARBA:ARBA00026227};
DE AltName: Full=GLE1 RNA export mediator {ECO:0000256|ARBA:ARBA00030897};
DE AltName: Full=GLE1-like protein {ECO:0000256|ARBA:ARBA00031503};
DE AltName: Full=Nucleoporin GLE1 {ECO:0000256|ARBA:ARBA00029983};
DE Flags: Fragment;
GN ORFNames=N326_13411 {ECO:0000313|EMBL:KFV97358.1};
OS Eurypyga helias (Sunbittern) (Ardea helias).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Eurypygimorphae; Eurypygiformes;
OC Eurypygidae; Eurypyga.
OX NCBI_TaxID=54383 {ECO:0000313|EMBL:KFV97358.1, ECO:0000313|Proteomes:UP000054232};
RN [1] {ECO:0000313|EMBL:KFV97358.1, ECO:0000313|Proteomes:UP000054232}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N326 {ECO:0000313|EMBL:KFV97358.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the export of mRNAs containing poly(A) tails
CC from the nucleus into the cytoplasm. May be involved in the terminal
CC step of the mRNA transport through the nuclear pore complex (NPC).
CC {ECO:0000256|ARBA:ARBA00024680}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nuclear pore complex
CC {ECO:0000256|ARBA:ARBA00004567}.
CC -!- SIMILARITY: Belongs to the GLE1 family.
CC {ECO:0000256|ARBA:ARBA00011056}.
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DR EMBL; KK554695; KFV97358.1; -; Genomic_DNA.
DR RefSeq; XP_010146120.1; XM_010147818.1.
DR AlphaFoldDB; A0A093IEX3; -.
DR GeneID; 104506756; -.
DR KEGG; ehs:104506756; -.
DR CTD; 2733; -.
DR OrthoDB; 317142at2759; -.
DR Proteomes; UP000054232; Unassembled WGS sequence.
DR GO; GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
DR GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.510; GLE1-like; 1.
DR InterPro; IPR012476; GLE1.
DR InterPro; IPR038506; GLE1-like_sf.
DR PANTHER; PTHR12960; GLE-1-RELATED; 1.
DR PANTHER; PTHR12960:SF0; MRNA EXPORT FACTOR GLE1; 1.
DR Pfam; PF07817; GLE1; 1.
PE 3: Inferred from homology;
KW mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW Nuclear pore complex {ECO:0000256|ARBA:ARBA00023132};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000054232};
KW Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT REGION 27..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 161..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 303..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..66
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..329
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..346
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV97358.1"
FT NON_TER 672
FT /evidence="ECO:0000313|EMBL:KFV97358.1"
SQ SEQUENCE 672 AA; 77140 MW; 7816FD3EB4049553 CRC64;
DILEGCMSPL VLSPYSGWVL DRVIERSAPE TSPSRSSASR ESSPHAKQSS PPEKMPSASH
RDPSPLSSAE PSEPKGNDDL NLPAMDEEVF PAVLPSKITE VEGCIWMYEE MHRLKGKEEL
RQRQEQQEQM VRAVYDLASE QLKRFDELKE LKQHQEFRDL QEVMEKSSKE SQGQQEKLKE
EHRHRAKVLN LRLREAEQQR QRQEELERSR KEEGQERLHR LYSIQEEVLQ LNKQIDPNYR
QKDLPKIDLS TYSNRGNQIC GLLSGLIRTT SERGFPTQAD VGSAERALQE MRGLISSMQQ
EIATAVEEKR KNEEEERQKQ KELLEKEESK AQTPAPAQQS GGKQQKEGPS LGLKADKNTM
EWYQKLQDAV EQCIASFSEL SNCKGNKEVK MIKTDLHKAA TIPVNQISRV SGSRLRDVFD
RLNNLLSGKS VQSGGRSVCV TQHPQGLDFV CYKLTEKLVG QAEEEVSSHR DAAFPIAVVV
SGIWELHPQV GDLFLAQLHK KCPYSVPFYP ALKEGTSMEE YQKILGYRFI DSKMENQDRF
LKRMSGMIRV YAAIIQLRWP FGNKQGAHPH GLEHGWRWLS QMLNMEPLVD LTATLLFDFL
EVCGNALMKQ YQVQFWKMML LIREDFVPRI EAITESREKG SLSRFKEFLE TCLKEKEIPL
PKGILQPSFW SS
//
