ID A0A093IFE6_EURHL Unreviewed; 474 AA.
AC A0A093IFE6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Rho GTPase-activating protein 20 {ECO:0000313|EMBL:KFW01435.1};
DE Flags: Fragment;
GN ORFNames=N326_12698 {ECO:0000313|EMBL:KFW01435.1};
OS Eurypyga helias (Sunbittern) (Ardea helias).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Eurypygimorphae; Eurypygiformes;
OC Eurypygidae; Eurypyga.
OX NCBI_TaxID=54383 {ECO:0000313|EMBL:KFW01435.1, ECO:0000313|Proteomes:UP000054232};
RN [1] {ECO:0000313|EMBL:KFW01435.1, ECO:0000313|Proteomes:UP000054232}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N326 {ECO:0000313|EMBL:KFW01435.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK561171; KFW01435.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093IFE6; -.
DR Proteomes; UP000054232; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd13319; PH_RARhoGAP; 1.
DR CDD; cd17115; RA_RHG20; 1.
DR CDD; cd04402; RhoGAP_ARHGAP20; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR047886; ARHGAP20-like_RhoGAP.
DR InterPro; IPR047887; ARHGAP20_PH.
DR InterPro; IPR047888; ARHGAP20_RA.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23179:SF36; RHO-GAP DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23179; T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00788; RA; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50200; RA; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000054232}.
FT DOMAIN 110..230
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT DOMAIN 280..466
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 238..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 254..276
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFW01435.1"
FT NON_TER 474
FT /evidence="ECO:0000313|EMBL:KFW01435.1"
SQ SEQUENCE 474 AA; 52855 MW; C0A846233B30C653 CRC64;
TFILDERVQL TVGLQTQERH LILFSDVLVI AKSKSSSSLK LKKQVHLSEV WTGTCLSEVT
EKKMSPENSF VIGWPTINYV VTFSSADTKE RWLSALLWHI NEVKQNEFLK NLTLQIFVLD
ADNCSSSAAV NVSNMETAES VMKKTLLQLG LPARTSEHHL WVISGKDDPA YPLIGHEYPF
SIALNCLRDS ADQQQGTNNN TLLADGTETS FFDQLPKEKQ CQFVLKPRLQ APMQLRRESL
QKHTKRKKSL IDWALRRSTS TPTGSPPSQS PTTPRKLFGL SLSSVCPDGI LPKPIMDMLL
LLYHKGPSTR GIFRRSANAK TCKELKEKLN SGDDVQVDGE SVFVAAAVIT DFLRNIPDSV
LSSDMHGLWM EAVDTENRAH KIEAIKSLVN QLPEANLILL RHLFGVLHHI EQNSGVNQMN
AFNLALCIAP NMLWLPSPTG PEEESRSTKK VALLVQFLIE NSGEIFGGDI ASLF
//
