ID A0A093IUT7_FULGA Unreviewed; 853 AA.
AC A0A093IUT7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Alpha-actinin-2 {ECO:0000313|EMBL:KFW02514.1};
DE Flags: Fragment;
GN ORFNames=N327_11849 {ECO:0000313|EMBL:KFW02514.1};
OS Fulmarus glacialis (Northern fulmar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Procellariiformes; Procellariidae;
OC Fulmarus.
OX NCBI_TaxID=30455 {ECO:0000313|EMBL:KFW02514.1, ECO:0000313|Proteomes:UP000053806};
RN [1] {ECO:0000313|EMBL:KFW02514.1, ECO:0000313|Proteomes:UP000053806}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N327 {ECO:0000313|EMBL:KFW02514.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the alpha-actinin family.
CC {ECO:0000256|ARBA:ARBA00010255}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KK594870; KFW02514.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093IUT7; -.
DR Proteomes; UP000053806; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd21214; CH_ACTN_rpt1; 1.
DR CDD; cd21216; CH_ACTN_rpt2; 1.
DR CDD; cd00051; EFh; 1.
DR CDD; cd00176; SPEC; 1.
DR Gene3D; 1.20.58.60; -; 4.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR014837; EF-hand_Ca_insen.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR11915:SF429; ALPHA-ACTININ-2; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF13499; EF-hand_7; 1.
DR Pfam; PF08726; EFhand_Ca_insen; 1.
DR Pfam; PF00435; Spectrin; 4.
DR SMART; SM00033; CH; 2.
DR SMART; SM00054; EFh; 2.
DR SMART; SM01184; efhand_Ca_insen; 1.
DR SMART; SM00150; SPEC; 2.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 4.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053806};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..101
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 110..216
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 712..747
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 748..783
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT COILED 231..258
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 630..657
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFW02514.1"
FT NON_TER 853
FT /evidence="ECO:0000313|EMBL:KFW02514.1"
SQ SEQUENCE 853 AA; 98675 MW; 83B0307408BFDDFB CRC64;
QTFTAWCNSH LRKAGTQIEN IEEDFRNGLK LMLLLEVISG ERLPKPDRGK MRFHKIANVN
KALDYIASKG VKLVSIGAEE IVDGNVKMTL GMIWTIILRF AIQDISVEET SAKEGLLLWC
QRKTAPYRNV NIQNFHLSWK DGLGLCALIH RHRPDLIDYS KLNKDDPIGN INLAMEIAEK
HLDIPKMLDA EDIVNTPKPD ERAIMTYVSC FYHAFAGAEQ AETAANRICK VLAVNQENER
LMEEYERLAS ELLEWIRRTI PWLENRTPEK TMQAMQKKLE DFRDYRRKHK PPKVQEKCQL
EINFNTLQTK LRISNRPAFM PSEGKMVSDI AGAWQRLEQA EKGYEEWLLN EIRRLERLEH
LAEKFRQKAS THEQWAYGKE QILLQKDYES ASLTEIRAML RKHEAFESDL AAHQDRVEQI
AAIAQELNEL DYHDAASVND RCQKICDQWD SLGTLTQKRR EALERTEKLL ETIDQLHLEF
AKRAAPFNNW MEGAMEDLQD MFIVHSIEEI QSLISAHDQF KATLPEADGE RQAILSIQNE
VEKVIQSYSM RISASNPYST VTVEEIRTKW EKVKQLVPQR DQSLQEELAR QHANERLRRQ
FAAQANVIGP WIQTKMEEIA RSSIEMTGPL EDQMNQLKQY EHNIINYKHN IDKLEGDHQL
IQEALVFDNK HTNYTMEHIR VGWELLLTTI ARTINEVETQ ILTRDAKGIT QEQMNDFRAS
FNHFDRRKNG LMDHDDFRAC LISMGYDLGE AEFARIMSLV DPNGQGTVTF QSFIDFMTRE
TADTDTAEQV IASFRILASD KPYILADELR RELPPEQAQY CIKRMPPYTG PGSVPGALDY
TSFSSALYGE SDL
//
