ID A0A093QCR7_9PASS Unreviewed; 1088 AA.
AC A0A093QCR7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 {ECO:0000313|EMBL:KFW86758.1};
DE Flags: Fragment;
GN ORFNames=N305_03619 {ECO:0000313|EMBL:KFW86758.1};
OS Manacus vitellinus (golden-collared manakin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Pipridae; Manacus.
OX NCBI_TaxID=328815 {ECO:0000313|EMBL:KFW86758.1, ECO:0000313|Proteomes:UP000053258};
RN [1] {ECO:0000313|EMBL:KFW86758.1, ECO:0000313|Proteomes:UP000053258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N305 {ECO:0000313|EMBL:KFW86758.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL672708; KFW86758.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093QCR7; -.
DR Proteomes; UP000053258; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd17902; ArfGap_ARAP3; 1.
DR CDD; cd17228; RA_ARAP3; 1.
DR CDD; cd04385; RhoGAP_ARAP; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 4.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR037858; RhoGAP_ARAP.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR45899:SF4; ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3; 1.
DR PANTHER; PTHR45899; RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C; 1.
DR Pfam; PF01412; ArfGap; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00788; RA; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SMART; SM00233; PH; 4.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 4.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50115; ARFGAP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 3.
DR PROSITE; PS50200; RA; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000053258};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 1..56
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 151..265
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT DOMAIN 478..576
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 580..761
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT DOMAIN 790..883
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT DOMAIN 896..998
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1069..1088
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFW86758.1"
FT NON_TER 1088
FT /evidence="ECO:0000313|EMBL:KFW86758.1"
SQ SEQUENCE 1088 AA; 124315 MW; 6A9B802BB0076A38 CRC64;
QEPYPKGVIP LSVIEMARSN KDNKFQVVTS HRIFVFRAEN EAQRNEWCST LQKKVMDQRL
VGSRPRPANT AHCQKSGTLE LKGQKSKVFA ALSLPEMWLY KSEQFFKMGI GMFFIEMRGS
TIREAKNRSF ELITPSKTFR YPRHPGGLRW EEQPEKIWSN KANKYCADCW AQSPDWASIN
LCVVICKQCA EQHRSLGSNI SKVQSLKLDT SVWSNEIVQL FIVLGNDRAN RFWAARLPAS
EAIHPDSSAE QRREFISRKY REGRYRLPHP HCPTQEDVLQ ALCTAVAGPT LLKTVLQFFS
SSEAGLASDP AASEVAPGAD LWWGLESKRP RNLSGSPRAR EPGLEGVYNE ITQPVTHSGY
LHRATAPPKL PGAKKSKEDF QRTWCSLERS LLFFETEKCT EPLGHIESGD LLSLGVSRAQ
ALTSPCPTER FRFTLELFLA GEKVQQLGTD GPETLQAWAS AIGKWFTPVS CHCLLGYEFQ
RVGQLRYKCM LNPERWQQAF FILQKAHLFI CPAEEDGAED SINLRRLQEL SLVPPTETPD
KKEMLILVEM GRTFYLQGLS RVDSAAWYTD IQASAGGRGN ALRDQQLSRG DIPIIVDSCI
AFITQYGLRH EGIYRKNGAK SRIKVLMEEF RRDARNVKLR INDNFIEDVT DVLKRFFREL
EDPIFTLELH PQWKEAAEIP SKPQRLERYK ELIHRLPRLN HKTLAALIGH LYRVQKCADL
NQMSTKNLSL LFAPSLFQTD GKGEHEVKVM EDLIDNYVSI FNIDEDQVSQ MDLENSLITT
WKDTQLSQAG DLIIEVYLEQ KLPDCCVTLK VSPTMTAEEL TNQVLEMRNV AASLDIWLTF
EALENGELER PLHPKEKVLE QALQWCKLPE PSAAYLLVRK VPIGEGSCLF TGAKRESPKC
GLLKCREEPP KLLGNKFQER YFVIRDRRLL LLKEKRSSKP EREWPLDAAK VYMGIKKKLK
PPAQWGFTLT LDKQQLCLVC SGQAELWDWT TSILKAQHDD RHPVILRRRS SSDLAKQKFG
TMPLVPLHGD STDATMLSAN QTLRRLHTRR TLSMFFPMKI HQDSLEEQQE KEVDADPVYE
EVGNFPEL
//
