ID   A0A093SW08_9PASS        Unreviewed;       728 AA.
AC   A0A093SW08;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   22-FEB-2023, entry version 41.
DE   SubName: Full=Ral guanine nucleotide dissociation stimulator-like 1 {ECO:0000313|EMBL:KFW86699.1};
DE   Flags: Fragment;
GN   ORFNames=N305_10546 {ECO:0000313|EMBL:KFW86699.1};
OS   Manacus vitellinus (golden-collared manakin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Pipridae; Manacus.
OX   NCBI_TaxID=328815 {ECO:0000313|EMBL:KFW86699.1, ECO:0000313|Proteomes:UP000053258};
RN   [1] {ECO:0000313|EMBL:KFW86699.1, ECO:0000313|Proteomes:UP000053258}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N305 {ECO:0000313|EMBL:KFW86699.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KL672661; KFW86699.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093SW08; -.
DR   Proteomes; UP000053258; Unassembled WGS sequence.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   CDD; cd00155; RasGEF; 1.
DR   CDD; cd06224; REM; 1.
DR   Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR   Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR008937; Ras-like_GEF.
DR   InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR   InterPro; IPR019804; Ras_G-nucl-exch_fac_CS.
DR   InterPro; IPR023578; Ras_GEF_dom_sf.
DR   InterPro; IPR001895; RASGEF_cat_dom.
DR   InterPro; IPR036964; RASGEF_cat_dom_sf.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR   PANTHER; PTHR23113:SF199; RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR-LIKE 1; 1.
DR   Pfam; PF00788; RA; 1.
DR   Pfam; PF00617; RasGEF; 1.
DR   Pfam; PF00618; RasGEF_N; 1.
DR   SMART; SM00314; RA; 1.
DR   SMART; SM00147; RasGEF; 1.
DR   SMART; SM00229; RasGEFN; 1.
DR   SUPFAM; SSF48366; Ras GEF; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS50200; RA; 1.
DR   PROSITE; PS00720; RASGEF; 1.
DR   PROSITE; PS50009; RASGEF_CAT; 1.
DR   PROSITE; PS50212; RASGEF_NTER; 1.
PE   4: Predicted;
KW   Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW   ECO:0000256|PROSITE-ProRule:PRU00168};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053258}.
FT   DOMAIN          11..142
FT                   /note="N-terminal Ras-GEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50212"
FT   DOMAIN          254..523
FT                   /note="Ras-GEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50009"
FT   DOMAIN          643..728
FT                   /note="Ras-associating"
FT                   /evidence="ECO:0000259|PROSITE:PS50200"
FT   REGION          534..591
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          608..628
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        534..567
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFW86699.1"
FT   NON_TER         728
FT                   /evidence="ECO:0000313|EMBL:KFW86699.1"
SQ   SEQUENCE   728 AA;  82205 MW;  3AF7E417BC43C034 CRC64;
     EHTVRQYETS KIRAIKAGTL EKLVENLLTA FGDADFSYIS IFLSTYRAFA STKAVLELLL
     DRFGNLETLS HGEVANLNSF ESEVTLRAEI ASVLRAWLDQ CSEDFREPPD HTCLLKLLDY
     LKNNMPNSDM ESKVQNLLKQ FQNQEAETVE PEHLSSLYSF FFHLFYANLI FWSFLSRMQH
     SGAITSGRTL GVFCCNTGMF QNKQAPALIH CLLCKFTECW FPSCPDGFCS TSSSDLVDGE
     ELEISNPEEF SSFQDHIVAE QLTYMDVMLF KKVVPYHCLG SIWSQRDKKE NKNLAPTVRA
     TITQFNTVTK CVVSTILGTK ELKIQQRAKI IEKWIHIAHE CRILKNFSSL RAIISALQSN
     SIYRLKTTWM CVSKDILLMY EELSEIFSDH DNYLTSRELL MKEATSKFAN LDSSEKENQK
     KSQKRLQLQK NKGVMQGTVP YLGTFLTDLI MLDTALQDYV EGGLINFEKR RREFEVIAQI
     KLLQSSCNSY CLIPDQKFIQ WFRSQRHLTE EESYKLSREV EAAADTNILS PKSQKSMVKR
     ISTTPSSGVS PLPSFPTLLP SSDDKSSVGS DKGYDSDKGS IGSDKGSGSN KCSIFDKGSG
     SDKYSIFDKA SGSDSGPVSD KSPGSTTCST SKVLPVYNRQ NGGACIIRVS MDGINDSVYK
     SILITNQDRI PDVTQRALLK HNLEPDAVED YELVQVISED KELVFPRDAN VFYGMNSHVN
     FDFILRKK
//