ID   A0A093XRZ4_9PEZI        Unreviewed;      1041 AA.
AC   A0A093XRZ4;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   08-NOV-2023, entry version 36.
DE   RecName: Full=Ras-GAP domain-containing protein {ECO:0000259|PROSITE:PS50018};
DE   Flags: Fragment;
GN   ORFNames=V490_06952 {ECO:0000313|EMBL:KFX89544.1};
OS   Pseudogymnoascus sp. VKM F-3557.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1437433 {ECO:0000313|EMBL:KFX89544.1, ECO:0000313|Proteomes:UP000029320};
RN   [1] {ECO:0000313|EMBL:KFX89544.1, ECO:0000313|Proteomes:UP000029320}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM F-3557 {ECO:0000313|EMBL:KFX89544.1,
RC   ECO:0000313|Proteomes:UP000029320};
RA   Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA   Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA   Ozerskaya S.M.;
RT   "Population genomics of a fungus Geomyces pannorum provides evidence of
RT   horizontal gene transfer but not of sexual reproduction.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFX89544.1}.
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DR   EMBL; JPJS01002072; KFX89544.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093XRZ4; -.
DR   STRING; 1437433.A0A093XRZ4; -.
DR   HOGENOM; CLU_003244_0_1_1; -.
DR   Proteomes; UP000029320; Unassembled WGS sequence.
DR   CDD; cd05137; RasGAP_CLA2_BUD2; 1.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR039360; Ras_GTPase.
DR   InterPro; IPR001936; RasGAP_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   PANTHER; PTHR10194:SF60; GTPASE-ACTIVATING PROTEIN; 1.
DR   PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR   Pfam; PF00616; RasGAP; 1.
DR   SMART; SM00323; RasGAP; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000029320}.
FT   DOMAIN          560..794
FT                   /note="Ras-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50018"
FT   REGION          1..60
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          187..206
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          381..406
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          956..1041
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..60
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        381..403
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1041
FT                   /evidence="ECO:0000313|EMBL:KFX89544.1"
SQ   SEQUENCE   1041 AA;  116149 MW;  B59C6EF5E447CD2A CRC64;
     MGSSDENISK EDPKPYVAHA STAFRSTQSQ RADSVKKKPQ TTGRLFRQSN TSSRSGSPVQ
     FPAYVDTLPI PIATRDAIKV LKLMNGLNGR MKGEVEYQTS GHGSWAGGVC YIDDKGTFLF
     EGTEDGPHHQ TIVKDLRGCR VRPPVDENEE NILDVSVASG MRLRLRLVDT SQYEYWLAAL
     LSWQQTQDSS SPSSSEAGER SLSRRPSFSQ AKDINIIKVG RVFLWDKGTF PSGSGGNNRG
     SRAWRQVSCI LQDNGELKLM TENDVSLLAT IQLSQLSRCG IQELDKTVLN QEYCVAILPQ
     YTAAATSISI VSPVFISLES RVLFEVWYVL LRTFTVPDMY GSQISADGSD DPDSLVIPAP
     DDLFRIEKTL SIRTIEAKLR PTGKKAEAPT DSRRGHKPEP DPSVGDYFAE VVLDGEVRSR
     TTTKFGTAKP FWREESEFGG LPAALPEISI ALKRMKSKPQ PHSQVHGSKS SVSVHTPEVV
     WEVLCGIVHI RMDQLDRGKD VENWWPVLNE KKEPIGEMLI RVRHDELVVL LQKEYSALSE
     LLHKFTMGLT LQMSQYVPSK LRFLAETLLD VFQVSGQASQ WLVSLVEDEI DGISKETPVQ
     RLRFSRRMGS NDSFDSVSDR EVQLRDMNKS LTGEANLLFR GNSLLTQALD FHMRRLGKEY
     LEDLLGDKVR EINALNPDCE VDPSRVGASE DLNRNWATLN ALTSDIWAHI SASHNQCPPE
     LRQILKYIRT VAEDRYGNFL RTAPYTSVSG FLFLRFFCPS LLNPKLFGLL RDHPHPRAQR
     TLTLIAKSLQ VLANLSTFGQ KEAWMEPMNR FLAQNRQTVK AFIDNICSIP ADRSRIPPPP
     SYSTPLAILK RLPMTSREGF PSLPYLIDEA RTYAALVRFW LEAVAGDTAR VAEFSGDLLA
     FHNECVALQK RADECLRRAE AEAKAEEPPE LKWTDILRSL ERSSALDQRT FTENDIVPHG
     ANATPQREAA RWNTRDDGMA VPGSAGSETG SRERRERQTF WESTFGKESS RAPRPLAVDA
     FGGSLDAGAA GASPPTDRGG S
//