ID   A0A093Y0N3_9PEZI        Unreviewed;      1018 AA.
AC   A0A093Y0N3;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 39.
DE   RecName: Full=Zn(2)-C6 fungal-type domain-containing protein {ECO:0000259|PROSITE:PS50048};
GN   ORFNames=V490_02311 {ECO:0000313|EMBL:KFX98453.1};
OS   Pseudogymnoascus sp. VKM F-3557.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1437433 {ECO:0000313|EMBL:KFX98453.1, ECO:0000313|Proteomes:UP000029320};
RN   [1] {ECO:0000313|EMBL:KFX98453.1, ECO:0000313|Proteomes:UP000029320}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM F-3557 {ECO:0000313|EMBL:KFX98453.1,
RC   ECO:0000313|Proteomes:UP000029320};
RA   Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA   Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA   Ozerskaya S.M.;
RT   "Population genomics of a fungus Geomyces pannorum provides evidence of
RT   horizontal gene transfer but not of sexual reproduction.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFX98453.1}.
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DR   EMBL; JPJS01000624; KFX98453.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093Y0N3; -.
DR   STRING; 1437433.A0A093Y0N3; -.
DR   HOGENOM; CLU_011671_0_0_1; -.
DR   Proteomes; UP000029320; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd12148; fungal_TF_MHR; 1.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 4.10.240.10; Zn(2)-C6 fungal-type DNA-binding domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR013752; KPA_reductase.
DR   InterPro; IPR013332; KPR_N.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   InterPro; IPR001138; Zn2Cys6_DnaBD.
DR   PANTHER; PTHR21708:SF30; 2-REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00740)-RELATED; 1.
DR   PANTHER; PTHR21708; PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR   Pfam; PF02558; ApbA; 1.
DR   Pfam; PF08546; ApbA_C; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF57701; Zn2/Cys6 DNA-binding domain; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   4: Predicted;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029320}.
FT   DOMAIN          426..459
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50048"
FT   REGION          340..362
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          375..418
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        375..394
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1018 AA;  111406 MW;  F0044E46953835C9 CRC64;
     MGSNAPKVNV CLIGSGGVGT IGSVVLENSG RARVTAVLRS KYKVVSEKGW DIESVDHGTL
     KGWKPSRIVA TVAEAALPPA GTPDDAHNYD YVFVSTKQLP DSYSVAELIR PVVTPGVTAV
     VLIQNGLDIE LPIIEAFPQN TVISGVSVIG SRTVGENGIA HIGSERVIMG PHFHDGLDRE
     TQIRQATDFV AMYDSGGPGI VSLDLDMPKA RWYKLLWNGT FNTLCALMKM DVGEVQSSKG
     RESLLVPMMR ELMAIAKEDG VELPEPVIQK LAYGLPDDCP YRPSMLVDVE QGRLMEIEVI
     LGNALKKAES CHTNCVVLPF NTAGGLWGKL VGPRPIMSEQ HATNMTGNGN VGGDQNQQQG
     GPEAAVVQNI IGNQANGSHE KDIGGSSQSL GAGSPEVSVA EESHGNSHEQ PRKRAKRIVR
     SMPGSSCLRC KVKKTKCEPS DTKERICKRC ESGNHECQYP IQRWAPRSDN LDIGFSDPSI
     SDSRSAAFEN HCAYESSFDA RADLQRKDAR IDRLEQTLSH YTALENQRMG GHASNNANVA
     AYALNPPQHH PTDTIPRGSN EMAYLDVIDH GILDLKTAHG LLQEFQSMNH NFPYIAINPN
     ISTGMLRRDS PMLLLAIYTA AAWKDRGLQI KLERAYLEEL ARRMVVDGEQ TLDMLQGLLV
     HLSWCHLHLK SSYRLTSLAI SLVTTLGINR RPMPADRQNL SVIFPFPKGA PAPSNSAKTW
     SLDARRAYIG AYVICSSYAH ALRKTSTLKY TPYLEECAQS LSSGSGLPSD VVLIHHVRLA
     HHVESISDTF DYDFSRSLPP VPDSQLSFHV RSFSAALTGI ESLIPTRLTG NSLLATSLHV
     VSAYTHEIGL HGLRPNDPLS LPRTTILIDC LGAVRRVLDA VVALNDVDFR ALFGYNWARI
     HYSLSLAVEL SLGVSSPSWG VENVRAVLAL ESYVDVFVQR LEGVSALVRK EGDQGDWFGF
     LAALWKELRR NYTEGMGSRG VVVPGEIPPV QELEGWLGLE DMDFMPNEWL WMVPAVGM
//