ID A0A093YB46_9PEZI Unreviewed; 603 AA.
AC A0A093YB46;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 13-SEP-2023, entry version 27.
DE RecName: Full=3-hydroxyacyl-CoA dehydrogenase NAD binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=O988_02290 {ECO:0000313|EMBL:KFY02251.1};
OS Pseudogymnoascus sp. VKM F-3808.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1391699 {ECO:0000313|EMBL:KFY02251.1, ECO:0000313|Proteomes:UP000029329};
RN [1] {ECO:0000313|EMBL:KFY02251.1, ECO:0000313|Proteomes:UP000029329}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-3808 {ECO:0000313|EMBL:KFY02251.1,
RC ECO:0000313|Proteomes:UP000029329};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY02251.1}.
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DR EMBL; JPJR01000366; KFY02251.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093YB46; -.
DR STRING; 1391699.A0A093YB46; -.
DR HOGENOM; CLU_031652_0_0_1; -.
DR Proteomes; UP000029329; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR InterPro; IPR006108; 3HC_DH_C.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR000033; LDLR_classB_rpt.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR48075:SF3; 3-HYDROXYACYL-COA DEHYDROGENASE; 1.
DR PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR Pfam; PF00725; 3HCDH; 1.
DR Pfam; PF02737; 3HCDH_N; 1.
DR SMART; SM00135; LY; 5.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF63825; YWTD domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000029329}.
FT DOMAIN 14..184
FT /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT /evidence="ECO:0000259|Pfam:PF02737"
FT DOMAIN 189..282
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
SQ SEQUENCE 603 AA; 65013 MW; 91FE900FAA67E010 CRC64;
MTSWTPPTTA GRPVTILGAG VLGRRIGLMC AAGGHDVHIR DPSTEQLEAA LSYIKDTLPS
ISQPAVTPGT ARAFTSIAEA ITNAWLVIEA IPEILPLKIS TFAELATIAP KDCILASNSS
SYKSSAMLDS VPEADRPRIL NMHFYMPPAV RVVELMTCGV THASIFPFLH AELANINMSP
VVVKKESTGF LFNRIWAAIK RECLTVIADG VGSPEDIDTV WTEMFGGAGG PCKLMDQVGL
DTVAHIEGHY VEERGFNPSA RDFVVREYVE KGKLGNKSED GGLYPPSSPK TSKPAAQDLY
ILDLGLTTLS APMASGRVLK GSADGKTPLT TLSTSESLPD GIVILNNRLY WTSMGPPSTN
TGSIRSSTLT GSDTTTIVPP GLIHTPKQIT ADPTTNHLYV SDREGMRVFR FRPDGSDLTT
LVQTGDFTNP AHKADQMRWC VGIAVDTQRR LVYWTQKGPS KGSRGRIMRA GYDIPAGETA
ESRSDIEVLF EGLPEPTDLE IDEEGEVLYW CDRGELPLGN TVNCASVAKG GKRVEGETEI
EKKLGYKIVV GGLHEAIGLQ VDVKNHVIYA SDLGGSVYRF NIDGTGKTRL YEEECAFAGI
ALI
//
