ID A0A093YQB2_9PEZI Unreviewed; 814 AA.
AC A0A093YQB2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 32.
DE RecName: Full=beta-glucosidase {ECO:0000256|ARBA:ARBA00012744, ECO:0000256|RuleBase:RU361161};
DE EC=3.2.1.21 {ECO:0000256|ARBA:ARBA00012744, ECO:0000256|RuleBase:RU361161};
GN ORFNames=V492_07503 {ECO:0000313|EMBL:KFY07039.1};
OS Pseudogymnoascus sp. VKM F-4246.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420902 {ECO:0000313|EMBL:KFY07039.1, ECO:0000313|Proteomes:UP000029299};
RN [1] {ECO:0000313|EMBL:KFY07039.1, ECO:0000313|Proteomes:UP000029299}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4246 {ECO:0000313|EMBL:KFY07039.1,
RC ECO:0000313|Proteomes:UP000029299};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC with release of beta-D-glucose.; EC=3.2.1.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000448,
CC ECO:0000256|RuleBase:RU361161};
CC -!- PATHWAY: Glycan metabolism; cellulose degradation.
CC {ECO:0000256|ARBA:ARBA00004987, ECO:0000256|RuleBase:RU361161}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336, ECO:0000256|RuleBase:RU361161}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY07039.1}.
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DR EMBL; JPJU01002657; KFY07039.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093YQB2; -.
DR STRING; 1420902.A0A093YQB2; -.
DR HOGENOM; CLU_004542_2_1_1; -.
DR UniPathway; UPA00696; -.
DR Proteomes; UP000029299; Unassembled WGS sequence.
DR GO; GO:0008422; F:beta-glucosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102483; F:scopolin beta-glucosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR026891; Fn3-like.
DR InterPro; IPR019800; Glyco_hydro_3_AS.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42715; BETA-GLUCOSIDASE; 1.
DR PANTHER; PTHR42715:SF5; BETA-GLUCOSIDASE M-RELATED; 1.
DR Pfam; PF14310; Fn3-like; 1.
DR Pfam; PF00933; Glyco_hydro_3; 2.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SMART; SM01217; Fn3_like; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
DR PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277,
KW ECO:0000256|RuleBase:RU361161};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361161};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361161};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326,
KW ECO:0000256|RuleBase:RU361161};
KW Reference proteome {ECO:0000313|Proteomes:UP000029299};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..814
FT /note="beta-glucosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001889628"
FT DOMAIN 736..802
FT /note="Fibronectin type III-like"
FT /evidence="ECO:0000259|SMART:SM01217"
FT REGION 208..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 814 AA; 87274 MW; EFAAD08D164EF25B CRC64;
MVSFTTKLAT ASCLSLSVFA GAASGQNITD DTHFYGQSPS VLPSPETPGT LSWQTAHAKA
VALVSQMTLA ERANITVGYE PTTGCSGATG SVPRLGWEGL CLADAGQGLR ATDFVNAYPA
GISVGTSWNK ALTLQRATHM AAEFKRKGVH VILGPVVGPL GRVALGGRNW EGFSNDPYLS
GSLVHDTIEG IQNAGVIASV KHFIGNEQEN NRNPIEPGTT GGGIGGGGGL SSGGPSNNLS
QTIESLSSNI DDKTMHELYL WPFADAIHAG SASVMCSYQR INNTYGCHNQ KTQNGLLKTE
LGFEGFVVSD WGAQHAGIAS AEGGLDMAMP DGGEFWGVDG SNLTTFVKNG SMPEARLTDM
ATRIVAAWYQ LGQDRDFPPV SLPIQYNVSH KAVNARDPAS KPILLQGAIE GHVLVKNVNK
TLPFKKPKLL SLFGYDAVAP PRVNLVDPNF NFKFGFLSNS EFFWKDAFVS PFVNPGQIGP
NGTLIVGGGS GGTAPAYISA PFDALQERAY TDNFQLLWDF HSTAPQVDQA SDACLVFINA
FATEGIDREG LHDDYSDDII LNVASACSNT VVVIHNAGVR LVDTWIDHPN ITAVMFAHLP
GQDSGRAAVS LLFGDESPSG KMTYTVAKNE SDYNVPLARA TDEFFFFPQD DFTEGVYIDY
RDFDRKNITP RYEFGFGLTY TTFEYSDLSV SLVQNASTSR DAPESPIIEG GKESLWDVIA
TASAVVTNTG DVTAKEVAQL YVHIPGGPVR QLRGFDKVEI APGESATVRF TLLRRDLSDW
NVAEQAWVLQ QGEYSVWVGA SSRNLPLTGE LTIS
//
