ID A0A093YVG8_9PEZI Unreviewed; 456 AA.
AC A0A093YVG8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=TFIIS N-terminal domain-containing protein {ECO:0000259|PROSITE:PS51319};
GN ORFNames=V492_05875 {ECO:0000313|EMBL:KFY08829.1};
OS Pseudogymnoascus sp. VKM F-4246.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420902 {ECO:0000313|EMBL:KFY08829.1, ECO:0000313|Proteomes:UP000029299};
RN [1] {ECO:0000313|EMBL:KFY08829.1, ECO:0000313|Proteomes:UP000029299}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4246 {ECO:0000313|EMBL:KFY08829.1,
RC ECO:0000313|Proteomes:UP000029299};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcription factor involved in RNA polymerase II
CC transcription regulation. May function in both SPT15/TBP post-
CC recruitment and recruitment steps of transcription.
CC {ECO:0000256|ARBA:ARBA00037349}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649}.
CC -!- SIMILARITY: Belongs to the IWS1 family.
CC {ECO:0000256|ARBA:ARBA00037992}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY08829.1}.
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DR EMBL; JPJU01002106; KFY08829.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093YVG8; -.
DR STRING; 1420902.A0A093YVG8; -.
DR HOGENOM; CLU_045275_1_0_1; -.
DR Proteomes; UP000029299; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR InterPro; IPR017923; TFIIS_N.
DR PANTHER; PTHR46010; PROTEIN IWS1 HOMOLOG; 1.
DR PANTHER; PTHR46010:SF1; PROTEIN IWS1 HOMOLOG; 1.
DR Pfam; PF08711; Med26; 1.
DR SUPFAM; SSF47676; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR PROSITE; PS51319; TFIIS_N; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00649}; Reference proteome {ECO:0000313|Proteomes:UP000029299}.
FT DOMAIN 271..348
FT /note="TFIIS N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51319"
FT REGION 1..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 372..456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..29
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..58
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..101
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..170
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 456 AA; 51014 MW; 3DAA68A0255A7AA9 CRC64;
MSDAGGSSRA ATPEDQGSPQ DTPIADVNEN SDAEQVEEND DQDDPDSELS EVDEAEFADF
DPTTVALGPV EIDEEVARTL KAGKRKRPDK DGEGAPKKPK EGKREKSKKR KERLERTQTG
AEEYDSGADG EILEGRRTAK PKSVRIEGER KERDRAKERK REEERVQAVD QENMTPEQRR
AAALDAAMDA ALKNPNKRRR KKDEVDLEEA FDEEIAALKI RMEQACQADN TARERSQPAV
HKLKMLPEVV ALLNRNTVRH SIVDPDTNFL LSVKFFLEPL NDGSLPAYNI QRDLFNALAQ
LPIEKEALLS SGIGKVVLYY TKSKRPEIGI KRIAERLLGE WSRPILKRSD DYKKRKIATK
EYDFQAAQLA LRPSGTQSSG QPSIGLSRKE LDRERVLAAP RPGNRARLET HSASYTVAPK
STFDPQRAMD PASRPIGASG MEAFRKMTAK KGTKRS
//
