ID A0A094B9U8_9PEZI Unreviewed; 887 AA.
AC A0A094B9U8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=DNA mismatch repair proteins mutS family domain-containing protein {ECO:0000259|PROSITE:PS00486};
GN ORFNames=V492_07438 {ECO:0000313|EMBL:KFY07112.1};
OS Pseudogymnoascus sp. VKM F-4246.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420902 {ECO:0000313|EMBL:KFY07112.1, ECO:0000313|Proteomes:UP000029299};
RN [1] {ECO:0000313|EMBL:KFY07112.1, ECO:0000313|Proteomes:UP000029299}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4246 {ECO:0000313|EMBL:KFY07112.1,
RC ECO:0000313|Proteomes:UP000029299};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY07112.1}.
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DR EMBL; JPJU01002640; KFY07112.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094B9U8; -.
DR STRING; 1420902.A0A094B9U8; -.
DR HOGENOM; CLU_002472_7_3_1; -.
DR Proteomes; UP000029299; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011184; DNA_mismatch_repair_Msh2.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR PANTHER; PTHR11361:SF21; MUTS PROTEIN HOMOLOG 4; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF005813; MSH2; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000029299}.
FT DOMAIN 646..662
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 834..887
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 835..852
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 887 AA; 99296 MW; 18CB9FB1DE5B157D CRC64;
MSSTPRPSTS YSARTTASHR HDGDTASTSQ FQSIQRSLSR ATSRPPTRTR SRAASSVFGG
QSQHIVCAVS ESRGVSPTVG LAFVNVSTGE AVMSQICDNQ FYVRTLLKLQ VFEPTEILLV
STSGPPNQKS KMYSLIEEEV IGSRIVCVDR RYWSEPAGVD FIQQLAFPED VEAIKVATEG
NFYATCCLAA SLRYIEYSLS ITFVSHSLRI KYQPSEGSMM IDLSTIQSLE LIQNITNAKS
KDCLFGLLNE TLTPMGSRML RSNILQPSTQ ENILKNRYDA VALKPFLDVD KLLTNLIIQP
TQPDIQHSEQ SINHILMLKT FVQCVGPVFE ALSSARSPLL VEIRSVCRPN NITPTLQIIG
EVINDDVTFQ RSPLDLRNQR TYAVKSGVNG LLDVARQTFK EATEDVHVHV SLINEKYETQ
METRYDNARR YYLRIPESNL EGRTLPDILI NCYRKKGYIE CQTLDLVKLN QRIEDSHQEV
VLMSDKTVTQ LIDNVRAEIQ PLFRVSDSIA MLDMLAAFAQ LVATSDYVKP EITRCLAIKS
GRHPVHEKAH SEKFIPNDVY ADKQKRFQII TGCNMSGKST YIRSIALMTV MAQIGSFVPA
QYASFPIVDQ LFARVSMDDC IEANVSTFAS EMRETAFILR NMGKNSLVII DELGRGTSTR
DGLAIALSIS EALVESHAFV WFTTHFRELG MLVLIPLYSL KLISPAQIMN ERAGVVNMHL
KVDISQDKMV MLYKIANGYV KEEHYGLSLA RVVNLPPLVL EVAEKVSNTL QAQAAANKKS
SKSFAIARKR KLVLSLREVL LQAQESAMQG KSLMEYLRKV QEEFVKRMDC IENEAENSDE
SVDGEEQSNE NYDSSNEDAQ HEGESNETED GTDESDMTGT DKTEMLV
//
