ID A0A094BKB2_9PEZI Unreviewed; 1036 AA.
AC A0A094BKB2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
GN ORFNames=V494_03674 {ECO:0000313|EMBL:KFY40063.1};
OS Pseudogymnoascus sp. VKM F-4513 (FW-928).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420907 {ECO:0000313|EMBL:KFY40063.1, ECO:0000313|Proteomes:UP000029288};
RN [1] {ECO:0000313|EMBL:KFY40063.1, ECO:0000313|Proteomes:UP000029288}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4513 (FW-928) {ECO:0000313|Proteomes:UP000029288};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000256|ARBA:ARBA00010992}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY40063.1}.
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DR EMBL; JPJW01001218; KFY40063.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094BKB2; -.
DR HOGENOM; CLU_007729_0_0_1; -.
DR OrthoDB; 1741084at2759; -.
DR Proteomes; UP000029288; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015798; P:myo-inositol transport; IEA:UniProt.
DR GO; GO:0015791; P:polyol transmembrane transport; IEA:UniProt.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR PANTHER; PTHR48020:SF12; MFS DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48020; PROTON MYO-INOSITOL COTRANSPORTER; 1.
DR Pfam; PF13641; Glyco_tranf_2_3; 1.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029288};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 62..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..404
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..438
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 450..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 484..505
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 511..535
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 942..964
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 970..989
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1001..1022
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 65..539
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 1036 AA; 116247 MW; 7F42CFD29E17155D CRC64;
MELSNIRRGF QNAALVAHDA EFYDEVSRGS HNETYLPVQL TPDEKLALRN EKDHLFAQSK
GLYMTVLTVS IAAILQGWVQ SSINGATLLW PSEFGLLNKT DPNLERHDQW IVGLTNAAPF
LFAAILGCPL VDPINRRCGR KGTILVAAVL IFASSLGSAF SNNWVQLFVC RIFNGIGMGL
KASSTPILAA ETAVSRWRGS SALCWQLWVA FGLALGFAAN LIVNTASKRL SMKLQLGAPI
VPALLLMVSL WWCPESPRWH MMKGRNDRKD RKENYRKAYN IFLALRNTPL QAQRDFYLIH
KQIEIELKYM TADNDRAKAH SYANRISELF SSNLRLRSAL VAACTVNLAQ QLCGINVLAF
YSSDVFSKAG KSDDDSNKKL HDTVAYLYSF GFGAINFVFC IPAIRNIDTR GRRALLLRTL
PFMAIFLFAA AACFHIPAND NGSAQRIGPI ALFLFLFAAV YSPGMGPMPF TVASESFPLS
HREVGVAVSV GLNLFFAGLL SLFYLRIDDA FTSTGSLCLF ASFNLVAAAL IFLLLPETKE
RSLEELDKVF SIPIKKFMHH QLFEVLPYYV NYYILGKKVK LEELWDPNIG IELPPTIHDV
ESRWHPSWSA TATRRRSIAA IPPDGTDDGT DITRLGSHNA SQNNDARYGR LIGNLIGTYL
YRPYPILSRP KYSGNDVTVL IPTITDDMEE LRPHFLSILA TPIHQLVLVT TDIRKAKLLA
FSEDLADPRI KVYSTPIANK RTQLAAVIPL VRTAITVLVD DDVTWTHTIL PWLLAPFEIP
RNGSVGVGMA AIRIRTGSVL TRCINFLGAV YLERRNFEGA ATLTLDGGIS CMSGRTNALR
TCILQDEAFL NAFCYETFNG VPIATGDDKM ITRWLVQEEW GMYVQYHPEA QLLTTLESGW
KFIYQCQRWA GSSWRGNYKT LFVESNPWTV FKKQPWTFYA KYIAVFTSIG LITDPLTLYC
YYQIRPLLEP TSLWAGTSGW VVMSLLYLFT KTIKLKSLFI AYPKDLVFLP VSILFGLFHG
FIKMKAFCKD KGWLSR
//
