ID A0A094BKY7_9PEZI Unreviewed; 804 AA.
AC A0A094BKY7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
GN ORFNames=V492_04717 {ECO:0000313|EMBL:KFY11037.1};
OS Pseudogymnoascus sp. VKM F-4246.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420902 {ECO:0000313|EMBL:KFY11037.1, ECO:0000313|Proteomes:UP000029299};
RN [1] {ECO:0000313|EMBL:KFY11037.1, ECO:0000313|Proteomes:UP000029299}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4246 {ECO:0000313|EMBL:KFY11037.1,
RC ECO:0000313|Proteomes:UP000029299};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY11037.1}.
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DR EMBL; JPJU01001587; KFY11037.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094BKY7; -.
DR HOGENOM; CLU_399073_0_0_1; -.
DR Proteomes; UP000029299; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd05120; APH_ChoK_like; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR002575; Aminoglycoside_PTrfase.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR43791; PERMEASE-RELATED; 1.
DR PANTHER; PTHR43791:SF40; THIAMINE PATHWAY TRANSPORTER THI73; 1.
DR Pfam; PF01636; APH; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029299};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 70..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 423..444
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 456..477
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 70..482
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..25
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 804 AA; 89067 MW; C956F84D3AE7E179 CRC64;
MGTPTEDEKT TARAFESEEK RLETPPIAST ESTDSRELDR AFVYLAAQNQ SNLDSNVDLK
ALRRKVDWHI IPVMTACFAL QFVDKVLINY SGVMGIREEL HLVGNDFSNA SSVFYISYLI
AMVPNVYILQ KVTVTKWLNI LAVLWGIATA CTAATSNYNS LLATRIFAGL FESPVSACLM
LISSQWYNSQ EQASRYSLWF CGMGVAQVAG AFISYGFQHV HSTTGLSSWR IMYLVLGLLT
SLVGVVGYII LPSSPMSAKF LTDSEKVALL NHIAANQTGI ENRHFKWRQL KEAALDAQIW
LLLLMAVSIT CSSGVISSYS STVIVNLGYS SPQAALLSSP SGLVNIIATV IAGFSIRFGA
NRWAWIAALC VPGMVGGALM SFAPHSMPAA IIIGTNLVSA IAPTLMLTFQ WAMSNCVGQT
KRVVASAVVS GGFAIGSIMG PQTFQDRDKP EYRPARISIL ATQGGAAFFA LLLFAYYSWA
NQRKDRVEAA LGPRSDNEEG RQVWGSKTDK ENLSTAAMAK ETLPSAATLI ARRLGRPPPK
TETRRLPQLS KEFLAQKDGS RETFVIHDFV ECQITLYPDD TVVKSGKRIH LDEKDALDLA
IGLNIPAPKV HDASIAADGI VSIRMDYIEG ETLEVLWPNM VEKDRQDICR QLRAIITTMQ
SVESKTGVIG SCNGGFFREC RRMGEYTGGP FQDEAGFNDY LTKLIGTTPT DINKALRSQL
RTDHRIVFAH GDLAQENIII KDMKIVAVVD WEYGGWFPEY WEYVKFFEVQ TNSGDWREYA
KYIFPQTYYN QLAIYQGVLR WGYH
//
