ID A0A094EHX9_9PEZI Unreviewed; 905 AA.
AC A0A094EHX9;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 18.
DE RecName: Full=Catalase {ECO:0000256|RuleBase:RU000498};
DE EC=1.11.1.6 {ECO:0000256|RuleBase:RU000498};
GN ORFNames=V499_08552 {ECO:0000313|EMBL:KFY71260.1};
OS Pseudogymnoascus sp. VKM F-103.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420912 {ECO:0000313|EMBL:KFY71260.1, ECO:0000313|Proteomes:UP000029295};
RN [1] {ECO:0000313|EMBL:KFY71260.1, ECO:0000313|Proteomes:UP000029295}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-103 {ECO:0000313|EMBL:KFY71260.1,
RC ECO:0000313|Proteomes:UP000029295};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Occurs in almost all aerobically respiring organisms and
CC serves to protect cells from the toxic effects of hydrogen peroxide.
CC {ECO:0000256|RuleBase:RU004142}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.6;
CC Evidence={ECO:0000256|RuleBase:RU000498};
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SIMILARITY: Belongs to the catalase family.
CC {ECO:0000256|ARBA:ARBA00005329, ECO:0000256|RuleBase:RU000498}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY71260.1}.
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DR EMBL; JPKB01001320; KFY71260.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094EHX9; -.
DR HOGENOM; CLU_014929_0_0_1; -.
DR Proteomes; UP000029295; Unassembled WGS sequence.
DR GO; GO:0004096; F:catalase activity; IEA:UniProtKB-EC.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR CDD; cd08157; catalase_fungal; 1.
DR Gene3D; 2.40.180.10; Catalase core domain; 1.
DR InterPro; IPR018028; Catalase.
DR InterPro; IPR024708; Catalase_AS.
DR InterPro; IPR011614; Catalase_core.
DR InterPro; IPR002226; Catalase_haem_BS.
DR InterPro; IPR010582; Catalase_immune_responsive.
DR InterPro; IPR020835; Catalase_sf.
DR PANTHER; PTHR11465; CATALASE; 1.
DR PANTHER; PTHR11465:SF26; CATALASE 2; 1.
DR Pfam; PF00199; Catalase; 1.
DR Pfam; PF06628; Catalase-rel; 1.
DR PRINTS; PR00067; CATALASE.
DR SMART; SM01060; Catalase; 1.
DR SUPFAM; SSF56634; Heme-dependent catalase-like; 1.
DR PROSITE; PS00437; CATALASE_1; 1.
DR PROSITE; PS00438; CATALASE_2; 1.
DR PROSITE; PS51402; CATALASE_3; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|RuleBase:RU000498};
KW Hydrogen peroxide {ECO:0000256|ARBA:ARBA00023324,
KW ECO:0000256|RuleBase:RU000498};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU000498};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000498};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU000498};
KW Peroxidase {ECO:0000256|ARBA:ARBA00022559, ECO:0000256|RuleBase:RU000498}.
FT DOMAIN 15..404
FT /note="Catalase core"
FT /evidence="ECO:0000259|SMART:SM01060"
SQ SEQUENCE 905 AA; 100111 MW; ACFC893BB22BB3B8 CRC64;
MAHSQNPPVF TLAEARTIGQ PIADPSNSTV LPARFGGGSL ALLQDTLLIE TLAHFNRERI
PERVVHARAA AAWGEFEVTH DISHLTTAKF LNGIGKKTKV LQRISTVGGA TGSAETVRDV
RGFSVKFFTE EGNHDIVGND IPVFFVRDPV KFPSLNRSHK KNPRSNTADE TMFWDFHVNN
QEGVHALMHL FGSRGIPASL RNINGFGVHT YKLVAVDGSF KYCKFHFKPI GGVQNMSPED
AAKNAGENAD YHTADLFNAI ENGYYPVWTL YVQVMEPKVA ETYPVNIFDI TKTWPHKDFP
LLPVGNMTLN KNPHNYFEDV EQAAFSPSNM VPGIAVTPDP MLQARMFAYP DAQRYRLGVN
YQQLASNRAL SRVYTPYERD GAASFNGNYG GEPNYVRSDF TVAKPGQKSI EHDEWAGGKV
GIHEIPVSDA DFAQATELWN IFGTQPGEQE GFVKNVAGAI QDIPKKLQEG TIAMFSKVHP
DIGRKLQAEL NSAGKISASA QSQESARSYQ ILIFILNSRI RHVVNTTTNK LAVDSFLFKI
VIMTKPVGKV KLDTRVAIEG LFTRREVAPP STKMPKRVPR EKMHRREMIW ELIFDVQVSQ
DRTGIFVAAR PLTPIGIVSG ERCGPRASLP APTVFTGRPL RGTLVISHDK RQEEVFDVVQ
LTLQGEVQSI IRLSSGSYCK IKKPLILMSS VKVANEFEQI DAEDPHTVTY QTEFFFDIPD
FTTLPSSHGN NTPKRLPPSM RVVKSNFISA ATAEIHNSGS IAGTCDVTYK IAACVFAGGR
LKSDASREII LMPIEDKPPP LEPEDFGKEY RLVGATSLRP SWGLRKSLMV VVSSMEPRPL
TFSNREEGCE STEVLLHLKT EGLSDGNKSR SSDIFFSGRA KGSYVNGRGT AISVGCVEED
KVRNK
//
