ID   A0A094H8H7_9PEZI        Unreviewed;       357 AA.
AC   A0A094H8H7;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=Opine dehydrogenase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=V499_00598 {ECO:0000313|EMBL:KFY80567.1};
OS   Pseudogymnoascus sp. VKM F-103.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1420912 {ECO:0000313|EMBL:KFY80567.1, ECO:0000313|Proteomes:UP000029295};
RN   [1] {ECO:0000313|EMBL:KFY80567.1, ECO:0000313|Proteomes:UP000029295}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM F-103 {ECO:0000313|EMBL:KFY80567.1,
RC   ECO:0000313|Proteomes:UP000029295};
RA   Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA   Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA   Ozerskaya S.M.;
RT   "Population genomics of a fungus Geomyces pannorum provides evidence of
RT   horizontal gene transfer but not of sexual reproduction.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate
CC         + H(+) + NADH; Xref=Rhea:RHEA:11092, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57540, ChEBI:CHEBI:57597, ChEBI:CHEBI:57642,
CC         ChEBI:CHEBI:57945; EC=1.1.1.8;
CC         Evidence={ECO:0000256|ARBA:ARBA00001662};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFY80567.1}.
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DR   EMBL; JPKB01000062; KFY80567.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A094H8H7; -.
DR   HOGENOM; CLU_056511_0_0_1; -.
DR   Proteomes; UP000029295; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0046168; P:glycerol-3-phosphate catabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR011128; G3P_DH_NAD-dep_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003421; Opine_DH.
DR   PANTHER; PTHR38015; BLR6086 PROTEIN; 1.
DR   PANTHER; PTHR38015:SF1; OCTOPINE_DH DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01210; NAD_Gly3P_dh_N; 1.
DR   Pfam; PF02317; Octopine_DH; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          5..104
FT                   /note="Glycerol-3-phosphate dehydrogenase NAD-dependent N-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01210"
FT   DOMAIN          177..322
FT                   /note="Opine dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF02317"
SQ   SEQUENCE   357 AA;  39315 MW;  1E6A202C3BD6FED4 CRC64;
     MQLRVSIVGA GPAGFALAAD LDSRGTNVLV YSHPTHVRHA NYVVENGCLR ATGKIEGSTT
     LRVTFDMAEV IEFSKIIILT VPSTGQETVL REFKQFDLRQ HTVIAVPGNL FSLVADAEMK
     IGSILETNLS PYSCRMKEGE LAVMGKKNLF LIAALQTSSN PSFTAEIQRI FPMELKWCHN
     VIEVCLSNIN GVFHPLMMLM NAGRIESTSG EFLLYHDGLT RSVANAMLAV DRVRLEIGEA
     FGFKLDGVTQ TSNKCYNQTF TDLVDLAQNS PPHNKLKAPP TMDNRNISED VPDLLVFWCG
     LAEKLGIDAS PIKAVITLAE MASGADYMKT GRNLQKLNLE HLSRSELIER FGVPQTQ
//