ID A0A094HES3_9PEZI Unreviewed; 1286 AA.
AC A0A094HES3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 36.
DE RecName: Full=Clustered mitochondria protein homolog {ECO:0000256|HAMAP-Rule:MF_03013};
DE AltName: Full=Protein TIF31 homolog {ECO:0000256|HAMAP-Rule:MF_03013};
GN Name=CLU1 {ECO:0000256|HAMAP-Rule:MF_03013};
GN Synonyms=TIF31 {ECO:0000256|HAMAP-Rule:MF_03013};
GN ORFNames=V498_08458 {ECO:0000313|EMBL:KFY82777.1};
OS Pseudogymnoascus sp. VKM F-4517 (FW-2822).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420911 {ECO:0000313|EMBL:KFY82777.1, ECO:0000313|Proteomes:UP000029270};
RN [1] {ECO:0000313|EMBL:KFY82777.1, ECO:0000313|Proteomes:UP000029270}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4517 (FW-2822) {ECO:0000313|Proteomes:UP000029270};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: mRNA-binding protein involved in proper cytoplasmic
CC distribution of mitochondria. {ECO:0000256|HAMAP-Rule:MF_03013}.
CC -!- SUBUNIT: May associate with the eukaryotic translation initiation
CC factor 3 (eIF-3) complex. {ECO:0000256|HAMAP-Rule:MF_03013}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03013}.
CC -!- SIMILARITY: Belongs to the CLU family. {ECO:0000256|HAMAP-
CC Rule:MF_03013}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY82777.1}.
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DR EMBL; JPKA01003154; KFY82777.1; -; Genomic_DNA.
DR HOGENOM; CLU_003256_2_0_1; -.
DR Proteomes; UP000029270; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007005; P:mitochondrion organization; IEA:UniProtKB-UniRule.
DR GO; GO:0051640; P:organelle localization; IEA:UniProt.
DR CDD; cd15466; CLU-central; 1.
DR Gene3D; 3.30.2280.10; Hypothetical protein (hspc210); 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR HAMAP; MF_03013; CLU; 1.
DR InterPro; IPR033646; CLU-central.
DR InterPro; IPR025697; CLU_dom.
DR InterPro; IPR028275; CLU_N.
DR InterPro; IPR027523; CLU_prot.
DR InterPro; IPR023231; GSKIP_dom_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12601:SF6; CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG; 1.
DR PANTHER; PTHR12601; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3; 1.
DR Pfam; PF13236; CLU; 1.
DR Pfam; PF15044; CLU_N; 1.
DR Pfam; PF12807; eIF3_p135; 1.
DR Pfam; PF13374; TPR_10; 2.
DR Pfam; PF13424; TPR_12; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF103107; Hypothetical protein c14orf129, hspc210; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS51823; CLU; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_03013};
KW RNA-binding {ECO:0000256|HAMAP-Rule:MF_03013};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 342..586
FT /note="Clu"
FT /evidence="ECO:0000259|PROSITE:PS51823"
FT REPEAT 1011..1044
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 639..668
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 902..943
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1213..1286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1216..1237
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1252..1269
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1286 AA; 141763 MW; 7AC0FA15FADCC224 CRC64;
MAESNDTKGQ SPALAQEAVA EPENAVTESH TTANGEAQEG EEELDQGAET IFSLTVNLPH
KPHKMQIMVS SQEQVHDVRQ SVIELPDTFQ YSCFHLEHNG ERINDFIQLS DVKDLVPESE
LKLVEDPYTE KEARIHVIRV RELIGAAGDR TDTLQGILSG LSLYDSVTES EAPASGEAAA
AQTNGAAHPL ADYDFEAPGA LSTLLPPTQE SHPKTIKAVG LSPWNPPPYH LRQKGHLLYL
QATTLEGEQF QITSHVSGFY VNKSTNGRFD PTPRTAPKSH AAHSLLALIS DLSPSFEPAF
EKLQEYNNLK EPLTNFQITN ATPASPWIVP SESSPLTTHQ SDLTRSQESY LISGIENTET
LRDWNEEFQS TRELPKETAQ DRVFRERLTS KLFADYNDAA ARGAVLVARG EVAPLNPTES
RDAQIFVYNN VFFSFGADGV GTFASEGGDE AARVATGKDV MGVRMVNQLD IDGLFTPGTV
VIDYLGKRLV GQSIVPGIFK QRDPGENQID YGAVDGKEVI AADEKFVPVF EKLSKALKVK
KHAVWDKAGK RHELEGSVET KGLLGTDGRK YVLDLYRVTP LDIEWMEESG TAISSPEQTS
EASYPHRMTV LRPELVEAYW KIKMRAWVNE RLEERRQAAK AEEDAKKAVT EGEADAESSE
TPAKPADSDR IDITDFAFSL NPDVFSGQEP QTEAEIAEWA KDEEEVRSAG KFLRDTVLPE
LVRDLKEGDV GFPMDGESLS RLLHKRGINI RYLGTLAGQA EGRRLEALKI LSIQEMISRS
FKHIAGNYLR YLPIPFTSAC IAHLLNCLLG TGFNESPVAL IDASLKALYA DTDLSFKDVT
PESLRKEIEA QTLKRYKYTL EENWFAAIKP VQMLREVSLK MGFQLVSKDY FFTKEAAANA
KPTKAVEAPK EATNGTATTA SSKKKKKARS DSPSAAKAVP AGPPMTFSAD DVLNVVPIIK
EASPKSALAE EALEAGRISI LQGQKKLGQE LLLESLSLHE QIYGIMHPEV ARVYNTLSML
YYQLEEKDAA VELARKAVIV SERTLGVDSA ETLLSYLNLG LFSHANGETK LALAYIKHAL
QLWKVIYGQN HPDSITTTNN AAVMLQHLKL YHESRLWFEA SLEICESVFG KQSINAGTLL
FQLAQALALD QDSKASVNRM RESYNIFLTE LGAEDKNTKE AESWLEQLTQ NAVSIAKHAK
DVQARRIRAG IKMSPGMSLG QTQAQPPVGQ TAEASSGRDP RNAMGMDSRS IDELLKFIEG
KEAKKPSSKK RPGQNNPKRR GGASKA
//
