ID   A0A094HIF7_9PEZI        Unreviewed;      1077 AA.
AC   A0A094HIF7;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=CNH domain-containing protein {ECO:0000259|PROSITE:PS50219};
GN   ORFNames=V500_09716 {ECO:0000313|EMBL:KFY84012.1};
OS   Pseudogymnoascus sp. VKM F-4518 (FW-2643).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1420913 {ECO:0000313|EMBL:KFY84012.1, ECO:0000313|Proteomes:UP000029284};
RN   [1] {ECO:0000313|EMBL:KFY84012.1, ECO:0000313|Proteomes:UP000029284}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM F-4518 (FW-2643) {ECO:0000313|Proteomes:UP000029284};
RA   Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA   Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA   Ozerskaya S.M.;
RT   "Population genomics of a fungus Geomyces pannorum provides evidence of
RT   horizontal gene transfer but not of sexual reproduction.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFY84012.1}.
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DR   EMBL; JPKC01002623; KFY84012.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A094HIF7; -.
DR   STRING; 1420913.A0A094HIF7; -.
DR   HOGENOM; CLU_004190_1_1_1; -.
DR   Proteomes; UP000029284; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR   InterPro; IPR001180; CNH_dom.
DR   InterPro; IPR032914; Vam6/VPS39/TRAP1.
DR   InterPro; IPR019452; VPS39/TGF_beta_rcpt-assoc_1.
DR   InterPro; IPR019453; VPS39/TGF_beta_rcpt-assoc_2.
DR   PANTHER; PTHR12894; CNH DOMAIN CONTAINING; 1.
DR   PANTHER; PTHR12894:SF27; TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1; 1.
DR   Pfam; PF00780; CNH; 1.
DR   Pfam; PF10366; Vps39_1; 1.
DR   Pfam; PF10367; Vps39_2; 1.
DR   PROSITE; PS50236; CHCR; 1.
DR   PROSITE; PS50219; CNH; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000029284}.
FT   DOMAIN          18..341
FT                   /note="CNH"
FT                   /evidence="ECO:0000259|PROSITE:PS50219"
FT   REGION          52..71
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          447..480
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          497..529
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          869..889
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1053..1077
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        52..69
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        452..470
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        497..518
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1077 AA;  117946 MW;  DBBA484DF9065A77 CRC64;
     MLSAFIARPI VELKARDKSK IESILAYGDR LIVGLSTGSL RIYRVNEPTV DVQNHNAEGP
     SSGQPTAPST AKPVDLLREL DKFSPRAIEQ LSRIKEANIL ISLSNYVVSI HDLQTYELQE
     QLPKTKNATT FAITSNIVKD TTTGIPEIIS RLGVAVKRRL LVWSWHESEL SPDVVEITLA
     AAIRTLSWAS ATKIICGMNS GYVIVDIISQ EIDDIVGPGA IGGPGASDAG RFGGVGSTSM
     GYMGLGGYTP KPLITRLRDG EILLAKDINS LFTDTAGKPL EKRQIPWQQA PESIGYSYPY
     LLSLQPALKG ILEIRNPETL SVLQQVSLPS ASIMHFPPPT VSLSHAGKGF HVASDRCIWR
     MEATDYDSQI TELVDGGQYD EAITILDTLE DALLQDKDGR LREIKMQKAQ LLFDQRKYRA
     ALGLFTEVSA PPERVIRLYP KVIAGSLSTI PDPEEPEEEG DHDEDGIGQD DQTADISTVG
     SPMKGFVNNF MKQHKKTPSD AASITSLKSG QKGDSDGSET ASLKTKHVED GPLEGKDLIS
     AVRELNAFLV DTRTRLQRFI EPGGGGLKIH PASAQNGTSK AAFESLLVSP SSSEDTEIEK
     KLIETATLVD TTLFRAYMLV QPSLAGSLFR LPNFCEPEVV NEKLLENNRY NDLVDFFHGK
     KLHREALELL KRFGEAEPSE ESGPTLQGPQ RTVGYLQNLQ PEAIDLILEF AEWPLRTDPD
     LGMEVFLADT ENAETLPRDK VVDFLEGIDT SLVVKYLEHV INELNDLTPS FHNRLANAYI
     QELSSRKDRT SGSWRTLMQQ SLDFLRSSKQ YSPLKAFGSI PRDDPDFYEA QAVVLSSMEQ
     HKQALEIYVF KIKDFDKAEN YCNSVYLHSE SSDSSTNRLE PTSNSTDSSP SIYHTLLSLY
     LTPQPPQEPN WAPALDLLSK HGSRLPASNT LTLIPANLLV KDLESYFCGR IRAANSVVNE
     ARVVTGLRKS EVVRAQAGLL LGEDDGSGGR ADAAGSFNAV GTGSGRNRHV VVGEERVCGV
     CHKRLGRSVV SVLPDNTVVH YACSKRAVQR GVNPDGGMGD LKRNGGSAAR GLNRTVS
//