ID A0A094HJ77_9PEZI Unreviewed; 617 AA.
AC A0A094HJ77;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=3-hydroxyacyl-CoA dehydrogenase NAD binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=V502_05624 {ECO:0000313|EMBL:KFZ15420.1};
OS Pseudogymnoascus sp. VKM F-4520 (FW-2644).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420915 {ECO:0000313|EMBL:KFZ15420.1, ECO:0000313|Proteomes:UP000029308};
RN [1] {ECO:0000313|EMBL:KFZ15420.1, ECO:0000313|Proteomes:UP000029308}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4520 (FW-2644) {ECO:0000313|Proteomes:UP000029308};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFZ15420.1}.
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DR EMBL; JPKE01002141; KFZ15420.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094HJ77; -.
DR STRING; 1420915.A0A094HJ77; -.
DR HOGENOM; CLU_031652_0_0_1; -.
DR OrthoDB; 4517707at2759; -.
DR Proteomes; UP000029308; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 2.
DR InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR InterPro; IPR006108; 3HC_DH_C.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR48075:SF3; 3-HYDROXYACYL-COA DEHYDROGENASE; 1.
DR PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR Pfam; PF00725; 3HCDH; 1.
DR Pfam; PF02737; 3HCDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF63825; YWTD domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000029308}.
FT DOMAIN 14..184
FT /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT /evidence="ECO:0000259|Pfam:PF02737"
FT DOMAIN 189..282
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
FT REGION 276..295
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 617 AA; 66102 MW; 7565F656684B7239 CRC64;
MSSWTPPTTA GRPVAILGAG VLGRRMALMC IAGGHDVHIR DPSADQLDAA LSYIASTAPS
LTPPDVTPGT ARAFTSLSLA ITNAWLVIEA IPEILSLKTS TFAELAALAP QDCILASNSS
SYKSSAMLSA VPTADRPRIL NMHFFMPPAI RVVELMTCGV THPAIFPFLF AELTRLKLSP
VVVKRESTGF LFNRIWAAIK RECLTVIADG VGSPEDIDGT WTQMFGGAAG PCKLMDQVGL
DTVAHIEEHY IEERGFDPSA RDFVVKEYVD KGKLGNKSQS GGLYPPQPDA PPSAPAQALY
MLDLGLSNLS APLSSGRVLK GSTSGLTPLT ALSTSESLPD GITTLSTRLY WTCMASPPTN
TGSIRSSTLS GEDITTILPP GAVHTPKQIT ADRTNSYLYV SDREGMRVLR FRPDGSDLTT
LVQNGDFTNP ALTTLVQTGD FTNPAHKVDQ TRWCVGIAVD PIHRLMYWTQ KGPSKGSQGR
IMRAGLDIPE GETAGNRSDI EVLFSGLPEP TDLELDEEAE TLYWCDRGEL PLGNTVNCAS
VARGAEKAEE KTEMEKMLGY KIVVGGLHEA IGLQLDVKNG VIYASDLGGS VYRFNFDGSG
KEKIYEADCA FAGIALV
//
