ID A0A094HNP2_9PEZI Unreviewed; 770 AA.
AC A0A094HNP2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=WH2 domain-containing protein {ECO:0000259|PROSITE:PS51082};
GN ORFNames=V501_02875 {ECO:0000313|EMBL:KFZ15114.1};
OS Pseudogymnoascus sp. VKM F-4519 (FW-2642).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420914 {ECO:0000313|EMBL:KFZ15114.1, ECO:0000313|Proteomes:UP000029315};
RN [1] {ECO:0000313|EMBL:KFZ15114.1, ECO:0000313|Proteomes:UP000029315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4519 (FW-2642) {ECO:0000313|Proteomes:UP000029315};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SURF4 family.
CC {ECO:0000256|ARBA:ARBA00006945}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFZ15114.1}.
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DR EMBL; JPKD01001009; KFZ15114.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094HNP2; -.
DR STRING; 1420914.A0A094HNP2; -.
DR HOGENOM; CLU_338924_0_0_1; -.
DR Proteomes; UP000029315; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR InterPro; IPR045214; Surf1/Surf4.
DR InterPro; IPR002995; Surf4.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR23427; SURFEIT LOCUS PROTEIN; 1.
DR PANTHER; PTHR23427:SF2; SURFEIT LOCUS PROTEIN 1; 1.
DR Pfam; PF02077; SURF4; 1.
DR Pfam; PF02205; WH2; 1.
DR PROSITE; PS01339; SURF4; 1.
DR PROSITE; PS51082; WH2; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000029315};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 564..585
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 592..611
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 617..636
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 656..674
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 680..700
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 707..726
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 738..758
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 41..58
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 1..431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 448..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..32
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..116
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..161
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..187
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..306
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..371
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..413
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..492
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 770 AA; 80457 MW; C6CF691ED9252AFB CRC64;
MPPPPPPPPP PPPMMGGPPP PPPPPPGGAL PARPPAGATK TRGALLSDIG KGKQLRKAVT
NDRSAPIVGK TAGDSSGPPA GAPAIPGMGR PSGLAPPVPG NRMRSNSDQG RDSGSSGVEA
PPQLGGLFAG GMPKLKKRGG GVDTGANKDS TYASDPESSR TSAPRPPAAA APKIPTGAAP
PLPNNRPPAT SAGTAPGVVP SVANLRKTLG HAGPRPASSA SLRGPPPPIG KKPPPPPGSR
KPSSNVASGP PPLPPSAAPS VPSAPAPPPP PPPSVSAPRP PMNGRPRSEA PQPLHPPAPP
SLPPSNGANP SLAVQAAIRA AGQASPSSAP PPPPPSSPPS APSFSRPAPQ PPHIEAPPQL
PSAPPPPVSR QRSSQPMSTM LDASAYTLAP NGSTARPGGA QRSPLSQESG GRVNIQDIRW
RFQDESMLPK PREYTGTQKR YRAGRGSIRG ASSRHNTAVL RAQQPRSSTM AQIRGTAGYN
LGGQQFGGPS RTEASDPSPL DAIRQQTSKI EDALDTLSEP LKPYLPAIGR FLIVVTFLED
ALRIITQWSD QLAYLRDYRH IPTGLNHIFL IVNVIAMTSC SVLVISRKHS DYAVGGLIGV
VVTQALGYGL IFDLNFFLRN LSVMGGLLMV LSDSWVRKTK AFAGLPEIDE KDRKMYFQLA
GRVLLIFLFV GFVFSGTWSF WRVLVAALGF VACVMVVVGF KAKFSATMLV VILSIFNLLV
NNFWTLHEAH PHKDFAKYDF FQILSIVGGL LLLVNSGPGK YSIDEKKKVY
//
