ID A0A094I0U4_9PEZI Unreviewed; 588 AA.
AC A0A094I0U4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=V502_03006 {ECO:0000313|EMBL:KFZ20727.1};
OS Pseudogymnoascus sp. VKM F-4520 (FW-2644).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420915 {ECO:0000313|EMBL:KFZ20727.1, ECO:0000313|Proteomes:UP000029308};
RN [1] {ECO:0000313|EMBL:KFZ20727.1, ECO:0000313|Proteomes:UP000029308}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4520 (FW-2644) {ECO:0000313|Proteomes:UP000029308};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFZ20727.1}.
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DR EMBL; JPKE01001174; KFZ20727.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094I0U4; -.
DR STRING; 1420915.A0A094I0U4; -.
DR HOGENOM; CLU_010730_3_1_1; -.
DR OrthoDB; 5482027at2759; -.
DR Proteomes; UP000029308; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd07652; F-BAR_Rgd1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23176:SF138; RHO GTPASE ACTIVATOR; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00055; FCH; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW Reference proteome {ECO:0000313|Proteomes:UP000029308}.
FT DOMAIN 62..336
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 535..588
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 382..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 382..409
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 428..518
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 588
FT /evidence="ECO:0000313|EMBL:KFZ20727.1"
SQ SEQUENCE 588 AA; 64138 MW; 2A5B9AEF4CAD2E69 CRC64;
MENPPRDADQ QFSESHTASS QRPESSERMS SSTGAPTENA TTPSGNAPAS AAPAPTPGPY
TEQVQNVVNS EIGVQTLLNR LKQSVASAKE FALFLQKRSK LEEDHATGLR KISRITHDNL
RRPEHRQGSF IASYDEVTRI HERMADNGEQ FASSLYQMHN DMIEMAANVE RGRKHWKTTG
LSAEQRLVDA EAAMRKSKAK YDTLAEDYDR ARTGDRQATK KFGLKGPKSA AQHEEDLLRK
AQAADADYAA KVQAAQSVRH EHLSRGRPEA VKGLQDLINE CDSALALQMQ KFAAFNEKLL
LHNGMSVSPL KDQAGEAGKS TRSLREAILD INNEGDLNYF IASYSSQVPP RPAEIKYERH
PVMAPSAPPA ASAQRQSEIP QGFNTFNSRQ GTAGPAASTP PQQSPMGAAG PGFNQGGPPP
PAQQQQPYPP HERSFSQSQG RPQSRDNGSA GRMGNGNSMP HSAAAPSYSS SGPPQLQTLP
FQTAAPQTHP LQQNTPTHQA PPQQQQQHQY GQQQQRTVAA MDPSNLPPLK PVFGMNLEQL
FQRDGSPIPM VVYQCIQAVD LFGLEVEGIY RVSGTAAHVN KIKAIFNN
//
