ID A0A094L4E9_9GAMM Unreviewed; 658 AA.
AC A0A094L4E9;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=3-methylcrotonyl-CoA carboxylase {ECO:0000313|EMBL:KFZ29563.1};
GN ORFNames=IDAT_00180 {ECO:0000313|EMBL:KFZ29563.1};
OS Pseudidiomarina atlantica.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Idiomarinaceae; Pseudidiomarina.
OX NCBI_TaxID=1517416 {ECO:0000313|EMBL:KFZ29563.1, ECO:0000313|Proteomes:UP000053718};
RN [1] {ECO:0000313|EMBL:KFZ29563.1, ECO:0000313|Proteomes:UP000053718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCCC 1A10513 {ECO:0000313|EMBL:KFZ29563.1,
RC ECO:0000313|Proteomes:UP000053718};
RA Du J., Lai Q., Shao Z.;
RT "Draft genome sequence of Idiomarina sp. MCCC 1A10513.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=biotin; Xref=ChEBI:CHEBI:57586;
CC Evidence={ECO:0000256|ARBA:ARBA00001953};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFZ29563.1}.
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DR EMBL; JPIN01000001; KFZ29563.1; -; Genomic_DNA.
DR RefSeq; WP_034728995.1; NZ_JPIN01000001.1.
DR AlphaFoldDB; A0A094L4E9; -.
DR STRING; 1517416.IDAT_00180; -.
DR eggNOG; COG4770; Bacteria.
DR OrthoDB; 9763189at2; -.
DR Proteomes; UP000053718; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd06850; biotinyl_domain; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.30.700.40; -; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR005481; BC-like_N.
DR InterPro; IPR011764; Biotin_carboxylation_dom.
DR InterPro; IPR005482; Biotin_COase_C.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR005479; CbamoylP_synth_lsu-like_ATP-bd.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR InterPro; IPR011054; Rudment_hybrid_motif.
DR InterPro; IPR011053; Single_hybrid_motif.
DR PANTHER; PTHR18866; CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE; 1.
DR PANTHER; PTHR18866:SF33; METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF02785; Biotin_carb_C; 1.
DR Pfam; PF00289; Biotin_carb_N; 1.
DR Pfam; PF00364; Biotin_lipoyl; 1.
DR Pfam; PF02786; CPSase_L_D2; 1.
DR SMART; SM00878; Biotin_carb_C; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 1.
DR SUPFAM; SSF51246; Rudiment single hybrid motif; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
DR PROSITE; PS50979; BC; 1.
DR PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR PROSITE; PS00866; CPSASE_1; 1.
DR PROSITE; PS00867; CPSASE_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00409}.
FT DOMAIN 1..447
FT /note="Biotin carboxylation"
FT /evidence="ECO:0000259|PROSITE:PS50979"
FT DOMAIN 120..317
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT DOMAIN 576..651
FT /note="Lipoyl-binding"
FT /evidence="ECO:0000259|PROSITE:PS50968"
SQ SEQUENCE 658 AA; 71786 MW; 21F88F636AA70A31 CRC64;
MIAKLLIANR GEIACRIIRT ARHLGIRTVA VYSAADQQAQ HVQLADESVF IGPAPSAESY
LVVDKIIAAA KQTGADAIHP GYGFLSENEA FADACASNNI IFVGPPTSAI AAMGSKSAAK
SIMSEAEVPL VPGYHGNEQG LEKLLAEAEQ IGFPVLLKAA YGGGGKGMRI VESAKQFKEA
LASAKREAQA AFGNDKMLVE KYLTKPRHVE IQVFCDQHGN AVYLAERDCS VQRRHQKVIE
EAPAPALSER TRQAMGEAAV RAAQAIDYVG AGTVEFLLDT DNRFYFMEMN TRLQVEHPVT
EMVTGQDLVA WQLQVAAGEP LPLSQDQVQL HGHAFEARIY AEDPHNDFLP STGVLHHLRT
PNPAADVRID SGVVEGDEVS AYYDPMIAKL VVWGEDRATA LRKLLQALDS YRIAGVRTNI
DFLRSIARHR DFAQANLTTR FIEKHEKVLF ADYTEQQIQD HAVLAALAEN LLERPSAGAD
VWQQARGFRL NQPAQYALEL LYRDTPISVA LEQTGNGWRS QFDKRIWQAE LNGDCLSVSC
DGHGYQVYVM QDAQSITVFS QSANLHFQRH LVADTLSQEP AAGSMTAPMN GTIVEVLVQP
GDTVEAEQAL VIMEAMKMEY TIRAAHAGTV EQVFYGAGDL VSDGAELVSL STDTTGDA
//
