ID   A0A094PSC1_9ACTN        Unreviewed;       370 AA.
AC   A0A094PSC1;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   28-JUN-2023, entry version 20.
DE   SubName: Full=PTS mannose transporter subunit IIA {ECO:0000313|EMBL:KGA04891.1};
GN   ORFNames=GM43_5045 {ECO:0000313|EMBL:KGA04891.1};
OS   actinobacterium acMicro-4.
OC   Bacteria; Actinomycetota; Actinomycetes.
OX   NCBI_TaxID=1504317 {ECO:0000313|EMBL:KGA04891.1, ECO:0000313|Proteomes:UP000029304};
RN   [1] {ECO:0000313|EMBL:KGA04891.1, ECO:0000313|Proteomes:UP000029304}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Ghai R., Mizuno C.M., Picazo A., Camacho A., Rodriguez-Valera F.;
RT   "Key roles for freshwater Actinobacteria revealed by deep metagenomic
RT   sequencing.";
RL   Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KGA04891.1}.
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DR   EMBL; JNSD01000013; KGA04891.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A094PSC1; -.
DR   STRING; 1504317.GM43_5045; -.
DR   PATRIC; fig|1504317.4.peg.1011; -.
DR   Proteomes; UP000029304; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR   GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR   InterPro; IPR003352; PTS_EIIC.
DR   InterPro; IPR013014; PTS_EIIC_2.
DR   Pfam; PF02378; PTS_EIIC; 1.
DR   PROSITE; PS51104; PTS_EIIC_TYPE_2; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW   Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        26..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        58..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        88..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        140..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        278..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        323..344
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          22..353
FT                   /note="PTS EIIC type-2"
FT                   /evidence="ECO:0000259|PROSITE:PS51104"
SQ   SEQUENCE   370 AA;  38308 MW;  4BA4E2452E5A8FC5 CRC64;
     MSDFIPSGTG TQAGWRAGLQ KIGGNLAGMV IPNIGAFIAW GLLTALFIPT GWLPNEEFSS
     MVGPMILNLL PILIGYTGGR IVHGQRGAVI GAIATVGVIV GTDIPMFLGA MIIGPLMAWI
     LKYIDKVLDP ITPVGFEMLI GNFSLGIAGM LGSLLGFLAI GPIVSAITTV LGNGVSWLVD
     NGVLPIASVL IEPAKILFMN NAINHGVLGP LGVVQAEETG KSILFMLETN PGPGLGILLA
     FWLAGPKILR GSAPGAIIIH FLGGIHEIYF PYVLMRPLVV LAAILGGATG VATFMVTGVG
     LVATPSPGSI FAYMAVTPPG NHLGVLLGIA LSAAVSFVVG WFILRLSKVD ATEADFEAAK
     KRTKDLKAGK
//