ID A0A094ZHI7_SCHHA Unreviewed; 293 AA.
AC A0A094ZHI7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 13-SEP-2023, entry version 29.
DE SubName: Full=C85 protease (C85 family) {ECO:0000313|EMBL:KAF1315428.1};
DE SubName: Full=OTU domain-containing protein 3 {ECO:0000313|EMBL:KGB32314.1};
GN Name=OTUD3 {ECO:0000313|EMBL:KAH9588083.1};
GN ORFNames=MS3_00010646 {ECO:0000313|EMBL:KAH9588083.1}, MS3_0013449
GN {ECO:0000313|EMBL:KAF1315428.1}, MS3_00439
GN {ECO:0000313|EMBL:KGB32314.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB32314.1};
RN [1] {ECO:0000313|EMBL:KGB32314.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
RN [2] {ECO:0000313|EMBL:KAF1315428.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=31494670;
RA Stroehlein A.J., Korhonen P.K., Chong T.M., Lim Y.L., Chan K.G.,
RA Webster B., Rollinson D., Brindley P.J., Gasser R.B., Young N.D.;
RT "High-quality Schistosoma haematobium genome achieved by single-molecule
RT and long-range sequencing.";
RL Gigascience 8:0-0(2019).
RN [3] {ECO:0000313|EMBL:KAH9588083.1}
RP NUCLEOTIDE SEQUENCE.
RA Stroehlein A.J.;
RT "Chromosome-level genome assembly for S. haematobium.";
RL Submitted (JUN-2021) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:KAH9588083.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=35167626;
RA Stroehlein A.J., Korhonen P.K., Lee V.V., Ralph S.A., Mentink-Kane M.,
RA You H., McManus D.P., Tchuente L.T., Stothard J.R., Kaur P., Dudchenko O.,
RA Aiden E.L., Yang B., Yang H., Emery A.M., Webster B.L., Brindley P.J.,
RA Rollinson D., Chang B.C.H., Gasser R.B., Young N.D.;
RT "Chromosome-level genome of Schistosoma haematobium underpins genome-wide
RT explorations of molecular variation.";
RL PLoS Pathog. 18:0-0(2022).
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DR EMBL; AMPZ02000599; KAF1315428.1; -; Genomic_DNA.
DR EMBL; AMPZ03000003; KAH9588083.1; -; Genomic_DNA.
DR EMBL; KL250499; KGB32314.1; -; Genomic_DNA.
DR RefSeq; XP_012792084.1; XM_012936630.1.
DR AlphaFoldDB; A0A094ZHI7; -.
DR STRING; 6185.A0A094ZHI7; -.
DR EnsemblMetazoa; XM_012936630.2; XP_012792084.1; MS3_0013449.
DR GeneID; 24588259; -.
DR KEGG; shx:MS3_00010646; -.
DR CTD; 23252; -.
DR OrthoDB; 597214at2759; -.
DR Proteomes; UP000471633; Unassembled WGS sequence.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd22756; OTU_OTUD3-like; 1.
DR Gene3D; 3.90.70.80; -; 1.
DR InterPro; IPR003323; OTU_dom.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR PANTHER; PTHR12419; OTU DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12419:SF7; OTU DOMAIN-CONTAINING PROTEIN 3; 1.
DR Pfam; PF02338; OTU; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS50802; OTU; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:KAF1315428.1};
KW Protease {ECO:0000313|EMBL:KAF1315428.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000471633}.
FT DOMAIN 61..188
FT /note="OTU"
FT /evidence="ECO:0000259|PROSITE:PS50802"
SQ SEQUENCE 293 AA; 33622 MW; 4501BF8DA4BC4ED7 CRC64;
MGSKSKAHGN RKKCKKNNVY LEAQQDRASK VCCKGNDEND YYLKNDPSAP EFRQQLNQLG
LDFREVPSDG NCLFSSLSDQ LYGTITNHKE VREQAVLYIE KHKEEFEAFF DVKDRLNKLR
SLGTYGGHEC IIAISRHFSV YIIIHQLKQK PWLAGTPVID KTHVNVSSYP QLHLAYHNGE
HYSSVRVFGD NSSNPTRIRI CLSTDNSASC ASNTFDRKCV DYSSDGSDDK SSIHSCKNCD
RQSDKFSYCN TDYFQTFPLH RKLSKKEKRQ LRRRSLELSN SEFVIKSISA LHI
//
