ID A0A094ZHI8_SCHHA Unreviewed; 176 AA.
AC A0A094ZHI8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=High mobility group {ECO:0000313|EMBL:KAH9588456.1, ECO:0000313|EMBL:KGB33352.1};
DE SubName: Full=SWI/SNF-related chromatin binding protein {ECO:0000313|EMBL:KAF1320744.1};
GN Name=HMGB2_1 {ECO:0000313|EMBL:KAH9588456.1};
GN ORFNames=MS3_00005849 {ECO:0000313|EMBL:KAH9588456.1}, MS3_0011850
GN {ECO:0000313|EMBL:KAF1320744.1}, MS3_01527
GN {ECO:0000313|EMBL:KGB33352.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB33352.1};
RN [1] {ECO:0000313|EMBL:KGB33352.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
RN [2] {ECO:0000313|EMBL:KAF1320744.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=31494670;
RA Stroehlein A.J., Korhonen P.K., Chong T.M., Lim Y.L., Chan K.G.,
RA Webster B., Rollinson D., Brindley P.J., Gasser R.B., Young N.D.;
RT "High-quality Schistosoma haematobium genome achieved by single-molecule
RT and long-range sequencing.";
RL Gigascience 8:0-0(2019).
RN [3] {ECO:0000313|EMBL:KAH9588456.1}
RP NUCLEOTIDE SEQUENCE.
RA Stroehlein A.J.;
RT "Chromosome-level genome assembly for S. haematobium.";
RL Submitted (JUN-2021) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:KAH9588456.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=35167626;
RA Stroehlein A.J., Korhonen P.K., Lee V.V., Ralph S.A., Mentink-Kane M.,
RA You H., McManus D.P., Tchuente L.T., Stothard J.R., Kaur P., Dudchenko O.,
RA Aiden E.L., Yang B., Yang H., Emery A.M., Webster B.L., Brindley P.J.,
RA Rollinson D., Chang B.C.H., Gasser R.B., Young N.D.;
RT "Chromosome-level genome of Schistosoma haematobium underpins genome-wide
RT explorations of molecular variation.";
RL PLoS Pathog. 18:0-0(2022).
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DR EMBL; AMPZ02000439; KAF1320744.1; -; Genomic_DNA.
DR EMBL; AMPZ03000003; KAH9588456.1; -; Genomic_DNA.
DR EMBL; KL250544; KGB33352.1; -; Genomic_DNA.
DR RefSeq; XP_012793130.1; XM_012937676.1.
DR AlphaFoldDB; A0A094ZHI8; -.
DR STRING; 6185.A0A094ZHI8; -.
DR EnsemblMetazoa; XM_012937676.1; XP_012793130.1; MS3_0011850.
DR GeneID; 24589275; -.
DR KEGG; shx:MS3_00005849; -.
DR CTD; 24589275; -.
DR OrthoDB; 1222485at2759; -.
DR Proteomes; UP000471633; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd21978; HMG-box_HMGB_rpt1; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 2.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR48112; HIGH MOBILITY GROUP PROTEIN DSP1; 1.
DR PANTHER; PTHR48112:SF32; HIGH MOBILITY GROUP PROTEIN DSP1; 1.
DR Pfam; PF00505; HMG_box; 1.
DR Pfam; PF09011; HMG_box_2; 1.
DR PRINTS; PR00886; HIGHMOBLTY12.
DR SMART; SM00398; HMG; 2.
DR SUPFAM; SSF47095; HMG-box; 2.
DR PROSITE; PS50118; HMG_BOX_2; 2.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Reference proteome {ECO:0000313|Proteomes:UP000471633}.
FT DOMAIN 8..78
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 96..162
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 8..78
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 96..162
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 71..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 176 AA; 20616 MW; 0578342E2130032C CRC64;
MAEDKGKPKG AMNAYAAFLQ SMRADHKKKH PNVTLDFKAF SKECSEQWKN LSAKEKKKFK
DIAEKDKERY RCEMEHYEPP ADEGRSKKRK RDPDAPKKAL SAFFLFCNDE RPKVKSENPD
WKVSEVAKEL GKRWEHCKNK AKYESLAQVE KQRYEKAMQK YKAGKKSKTE DSESDD
//
