ID   A0A094ZPM8_SCHHA        Unreviewed;       797 AA.
AC   A0A094ZPM8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 {ECO:0000313|EMBL:KGB36665.1};
GN   ORFNames=MS3_04978 {ECO:0000313|EMBL:KGB36665.1};
OS   Schistosoma haematobium (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB36665.1};
RN   [1] {ECO:0000313|EMBL:KGB36665.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=22246508; DOI=10.1038/ng.1065;
RA   Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA   Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA   Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA   Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA   Wang J., Gasser R.B.;
RT   "Whole-genome sequence of Schistosoma haematobium.";
RL   Nat. Genet. 44:221-225(2012).
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DR   EMBL; KL250799; KGB36665.1; -; Genomic_DNA.
DR   RefSeq; XP_012796427.1; XM_012940973.1.
DR   AlphaFoldDB; A0A094ZPM8; -.
DR   STRING; 6185.A0A094ZPM8; -.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   CDD; cd18010; DEXHc_HARP_SMARCAL1; 1.
DR   CDD; cd18793; SF2_C_SNF; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038718; SNF2-like_sf.
DR   InterPro; IPR049730; SNF2/RAD54-like_C.
DR   InterPro; IPR000330; SNF2_N.
DR   PANTHER; PTHR45766; DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER; 1.
DR   PANTHER; PTHR45766:SF3; SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A-LIKE PROTEIN 1; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF00176; SNF2-rel_dom; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          164..329
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          439..597
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          28..51
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          633..662
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          686..716
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        639..659
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   797 AA;  90611 MW;  2A4B31D031AACEA5 CRC64;
     MARSWVNSGK PTTVKTTENL VKQQTQVKPN FLPKSSSNSF PSRTQSTPND AFRPKTSLVN
     VLCTLCSPNR FEVHARYHVG LTQLFKSMDS KQYVKKVNDI DELHLEELPY AVLKIFRRRI
     SMNFGADDLK DNENNDEIDH CTLKDRIPDD LLSTLFPFQK DGVCLALKRS GRVLLADDMG
     LGKTIQSLAI ASAYYSEWPL LIITPSSVRF SWRDQIIRWL GKPLNLNLTH ITVVNSGKDI
     MDDWDSFNSS PITIISYDLM SRYGKELLKR RYGVVIADES HFIKNIKAAR TKAATPILKW
     AKRVLLLSGT PAMSRPAELF PQISAISPNL FQGGFHEFGL RYCSAKECPW GWDYSGCSNM
     TELQLVLERS IMIRRVKADV LSQLPAKRRE LVVLDPSIIK KGSLGRHAKT MLTDKLSSKE
     KRSALFEYFH ATGSVKLPAI EQYVLDIIEC GHKFLLFAHH TDVLDSLDKL LSEKSIRFIR
     IDGRTNSEQR SVVCQIFQNE DDCRVALLSV TAAGTGLHLT AANLVIFAEL FWNPGVLVQA
     EDRAYRIGQM DSVLIRYLIA EQTADDFIWP LVERKLEVLS KAGLNRETFR MTDSTTRLGS
     NKLEQQKILD YFKEELNDFE EWENFDTVSS VINEESSNTH SQNDKKIDNN NDHQNKVKSK
     NDSLMNQIHS TEPKLTTSLF RAKSQSSVIN NTTPNKNNPR KRLLVPSSPE SNHSEIFSNE
     FNDNIDEDDL IWADDDDDGD FVEQIDESDI TDNNIEEFSG NDEYLLSEAV KIAEAAEVDW
     LTEGLIKEDT DDIEINQ
//