ID A0A094ZQ83_SCHHA Unreviewed; 181 AA.
AC A0A094ZQ83;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=ADP-ribosylation factor {ECO:0000256|RuleBase:RU369003};
GN Name=ARF4 {ECO:0000313|EMBL:KAH9586029.1};
GN ORFNames=MS3_00007086 {ECO:0000313|EMBL:KAH9586029.1}, MS3_0014383
GN {ECO:0000313|EMBL:KAF1335010.1}, MS3_03443
GN {ECO:0000313|EMBL:KGB35199.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB35199.1};
RN [1] {ECO:0000313|EMBL:KGB35199.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
RN [2] {ECO:0000313|EMBL:KAF1335010.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=31494670;
RA Stroehlein A.J., Korhonen P.K., Chong T.M., Lim Y.L., Chan K.G.,
RA Webster B., Rollinson D., Brindley P.J., Gasser R.B., Young N.D.;
RT "High-quality Schistosoma haematobium genome achieved by single-molecule
RT and long-range sequencing.";
RL Gigascience 8:0-0(2019).
RN [3] {ECO:0000313|EMBL:KAH9586029.1}
RP NUCLEOTIDE SEQUENCE.
RA Stroehlein A.J.;
RT "Chromosome-level genome assembly for S. haematobium.";
RL Submitted (JUN-2021) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:KAH9586029.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=35167626;
RA Stroehlein A.J., Korhonen P.K., Lee V.V., Ralph S.A., Mentink-Kane M.,
RA You H., McManus D.P., Tchuente L.T., Stothard J.R., Kaur P., Dudchenko O.,
RA Aiden E.L., Yang B., Yang H., Emery A.M., Webster B.L., Brindley P.J.,
RA Rollinson D., Chang B.C.H., Gasser R.B., Young N.D.;
RT "Chromosome-level genome of Schistosoma haematobium underpins genome-wide
RT explorations of molecular variation.";
RL PLoS Pathog. 18:0-0(2022).
CC -!- FUNCTION: GTP-binding protein involved in protein trafficking;
CC modulates vesicle budding and uncoating within the Golgi apparatus.
CC {ECO:0000256|RuleBase:RU369003}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000256|RuleBase:RU369003}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Arf family.
CC {ECO:0000256|ARBA:ARBA00010290, ECO:0000256|RuleBase:RU003925}.
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DR EMBL; AMPZ02000225; KAF1335010.1; -; Genomic_DNA.
DR EMBL; AMPZ03000004; KAH9586029.1; -; Genomic_DNA.
DR EMBL; KL250664; KGB35199.1; -; Genomic_DNA.
DR RefSeq; XP_012794964.1; XM_012939510.1.
DR AlphaFoldDB; A0A094ZQ83; -.
DR STRING; 6185.A0A094ZQ83; -.
DR EnsemblMetazoa; XM_012939510.1; XP_012794964.1; MS3_0014383.
DR GeneID; 24591048; -.
DR KEGG; shx:MS3_00007086; -.
DR CTD; 378; -.
DR OrthoDB; 5474610at2759; -.
DR Proteomes; UP000471633; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003924; F:GTPase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-UniRule.
DR CDD; cd04150; Arf1_5_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR045872; Arf1-5-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR11711; ADP RIBOSYLATION FACTOR-RELATED; 1.
DR PANTHER; PTHR11711:SF30; ADP-RIBOSYLATION FACTOR 1; 1.
DR Pfam; PF00025; Arf; 1.
DR PRINTS; PR00328; SAR1GTPBP.
DR SMART; SM00177; ARF; 1.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00178; SAR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51417; ARF; 1.
PE 3: Inferred from homology;
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892,
KW ECO:0000256|RuleBase:RU369003};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034,
KW ECO:0000256|RuleBase:RU369003};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU003925};
KW Lipoprotein {ECO:0000256|RuleBase:RU369003};
KW Myristate {ECO:0000256|ARBA:ARBA00022707, ECO:0000256|RuleBase:RU369003};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003925};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU369003};
KW Reference proteome {ECO:0000313|Proteomes:UP000471633};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU369003}.
SQ SEQUENCE 181 AA; 20734 MW; 4754321403B25C99 CRC64;
MGLTISSVFQ RLFGKKSMRI LMIGLDAAGK TTILYKLKLG EVVTTIPTIG FNVETVEYKN
INFTVWDVGG QDKIRRLWRH YFQNTQGLIF VVDSNDRDRI SESAEELNKM LLEDELRDVV
ILVFANKQDL PNAMSTAEVA EKLRLRDIRN RPWHIQLACA TQGEGLFEGL DWLSNELSKR
S
//
