ID A0A094ZRW5_SCHHA Unreviewed; 928 AA.
AC A0A094ZRW5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Integral membrane protein {ECO:0000313|EMBL:KGB36907.1};
GN ORFNames=MS3_00009592 {ECO:0000313|EMBL:KAH9579442.1}, MS3_0015105
GN {ECO:0000313|EMBL:KAF1330659.1}, MS3_05218
GN {ECO:0000313|EMBL:KGB36907.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB36907.1};
RN [1] {ECO:0000313|EMBL:KGB36907.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
RN [2] {ECO:0000313|EMBL:KAF1330659.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=31494670;
RA Stroehlein A.J., Korhonen P.K., Chong T.M., Lim Y.L., Chan K.G.,
RA Webster B., Rollinson D., Brindley P.J., Gasser R.B., Young N.D.;
RT "High-quality Schistosoma haematobium genome achieved by single-molecule
RT and long-range sequencing.";
RL Gigascience 8:0-0(2019).
RN [3] {ECO:0000313|EMBL:KAH9579442.1}
RP NUCLEOTIDE SEQUENCE.
RA Stroehlein A.J.;
RT "Chromosome-level genome assembly for S. haematobium.";
RL Submitted (JUN-2021) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:KAH9579442.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=35167626;
RA Stroehlein A.J., Korhonen P.K., Lee V.V., Ralph S.A., Mentink-Kane M.,
RA You H., McManus D.P., Tchuente L.T., Stothard J.R., Kaur P., Dudchenko O.,
RA Aiden E.L., Yang B., Yang H., Emery A.M., Webster B.L., Brindley P.J.,
RA Rollinson D., Chang B.C.H., Gasser R.B., Young N.D.;
RT "Chromosome-level genome of Schistosoma haematobium underpins genome-wide
RT explorations of molecular variation.";
RL PLoS Pathog. 18:0-0(2022).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AMPZ02000273; KAF1330659.1; -; Genomic_DNA.
DR EMBL; AMPZ03000008; KAH9579442.1; -; Genomic_DNA.
DR EMBL; KL250823; KGB36907.1; -; Genomic_DNA.
DR RefSeq; XP_012796669.1; XM_012941215.1.
DR AlphaFoldDB; A0A094ZRW5; -.
DR EnsemblMetazoa; XM_012941215.2; XP_012796669.1; MS3_0015105.
DR GeneID; 24592687; -.
DR KEGG; shx:MS3_00009592; -.
DR CTD; 24592687; -.
DR OrthoDB; 4259952at2759; -.
DR Proteomes; UP000471633; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR InterPro; IPR004776; Mem_transp_PIN-like.
DR PANTHER; PTHR22829; DEP DOMAIN PROTEIN; 1.
DR PANTHER; PTHR22829:SF5; INTEGRAL MEMBRANE PROTEIN GPR155; 1.
DR Pfam; PF03547; Mem_trans; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000471633};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 32..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 425..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 469..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 507..529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 549..571
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 722..744
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 764..785
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 608..628
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 928 AA; 104027 MW; 32FEF7DB54F710B1 CRC64;
MDNKPTSIRS SLPTATNSTV NYHEVFSELV PVLTQCFGVI LLGYIAGLLK IFSEPQAKGL
NLYVTRFALP IVFFRAMVII NFSGVCWSFV MAISISKLIG FIMAITFTYL ISRRFHLGIA
AIVAMFVSQT NDVALAYPIL YALFPDLASY IYLFAPIQLI VLNPFAYFLL ELERVRLTNS
ELKPLIHSED SDIDRRQLID GKSSNSVPSC GRCQQLTQVM FNVLKNPLIF MTLIGIIFNL
ILKHHLPVYI NGLLSVIADS FGATALFSLG YGMVGKMSTI TQREAYILTT ILLTKLLIVP
FITRELVVQM MPIALANETL RYSTFGFLYG TTPTAPPVFL FAAEYQVIPV AIGVGLVLGT
FLCVPIMFIS ARIITLYNAE PSDYASILGT TVEDISWISI VCCIWTLGVL CVSRKAIRVP
NRFTLCHLIC VLFTCTGLLL GRFVNYYYYG IEESVNGGKL SQPIRWLNYL HFAIFFFGST
GTRCWTTLIA LVLVMERARS LCFVLRYQLH IYLAGFLTPA VVTGLLLLTS FGHMVKDIDP
IFQCGTNQLI ISIVVLIVNA SGTLACLISF IRIDVPVQDC YEIKASPDVA EGICRSQLCR
NFNDFDKNDT DQTQQSQQTS PSNSIITDSY RITRNSDDSE LLSCRNSQIP QSCDSAKFCN
QCDKKQRKEC AKILARYCET DQPSMISSTS ATHPITQQIS LGLELDNVHA QGNNKPPHHK
HVIFLILILV TMFLGICLCT WRLVHDAPTG VYIVLEFLDG SFNFGQGVVL FALFGLDADL
FIAPIKRFLS RWFSHFTSKQ FNGSFNEALH QTTVDKNKID KIVNQFVKFH LKSCSTNIGT
GKIINSIHYE QIFYQYTLEQ WLIAAGITDS NEETLCYIEC LELGNIITCI SPMTNESFMN
KDTMTAISNT KRLLTFTAYA WGLHNISY
//
