ID   A0A095A499_SCHHA        Unreviewed;       369 AA.
AC   A0A095A499;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 40.
DE   SubName: Full=Male-specific lethal 3-like protein {ECO:0000313|EMBL:KGB40429.1};
GN   ORFNames=MS3_08897 {ECO:0000313|EMBL:KGB40429.1};
OS   Schistosoma haematobium (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB40429.1};
RN   [1] {ECO:0000313|EMBL:KGB40429.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=22246508; DOI=10.1038/ng.1065;
RA   Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA   Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA   Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA   Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA   Wang J., Gasser R.B.;
RT   "Whole-genome sequence of Schistosoma haematobium.";
RL   Nat. Genet. 44:221-225(2012).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; KL251463; KGB40429.1; -; Genomic_DNA.
DR   RefSeq; XP_012800187.1; XM_012944733.1.
DR   AlphaFoldDB; A0A095A499; -.
DR   STRING; 6185.A0A095A499; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 2.30.30.140; -; 1.
DR   Gene3D; 1.10.274.30; MRG domain; 1.
DR   InterPro; IPR016197; Chromo-like_dom_sf.
DR   InterPro; IPR008676; MRG.
DR   InterPro; IPR038217; MRG_C_sf.
DR   InterPro; IPR026541; MRG_dom.
DR   PANTHER; PTHR10880; MORTALITY FACTOR 4-LIKE PROTEIN; 1.
DR   PANTHER; PTHR10880:SF15; MRG DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF05712; MRG; 1.
DR   SUPFAM; SSF54160; Chromo domain-like; 1.
DR   PROSITE; PS51640; MRG; 1.
PE   4: Predicted;
KW   Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          177..366
FT                   /note="MRG"
FT                   /evidence="ECO:0000259|Pfam:PF05712"
SQ   SEQUENCE   369 AA;  42571 MW;  E84CDC21EF2EF076 CRC64;
     MDSRPHRYDI GQKLLCFEPD SSKAKLIYFA KILKHVSRRD TVVPHYCVHF HGWKCKWDRE
     VPEDLLLENN EFNRVLKRKI DEVHGRHQRK QRIDMILEGA ALSGDDIDWE TVPGVWKGSK
     SKISYHSSLS SDSNRGKTLI SSTSFDDNIP FLDPVLSSIL DQEEITQLQF EQLQIHKPYM
     VSLDLPQNLR DILKCHTDAS DVGTDVSKTF QYWCSVLQVL QKYVDGFPYS GLNISALLGC
     SSSSSGIISD RVSRIMNPLF SLTDRNRLIC AEVCSSLRIL FDFTVKSYLL LPNEKLYFTN
     DFNGHLFEDG RAFSVNYHHG PNDIHSIYRF SSPRYELLPN SEVIKNPRLP CLNYPPYYLL
     RLISRLSVN
//