ID A0A095AEZ3_SCHHA Unreviewed; 769 AA.
AC A0A095AEZ3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=DRBM domain-containing protein {ECO:0000259|PROSITE:PS50137};
GN ORFNames=MS3_00002266 {ECO:0000313|EMBL:KAH9596657.1}, MS3_0015837
GN {ECO:0000313|EMBL:KAF1338798.1}, MS3_00541
GN {ECO:0000313|EMBL:KGB32421.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB32421.1};
RN [1] {ECO:0000313|EMBL:KGB32421.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
RN [2] {ECO:0000313|EMBL:KAF1338798.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=31494670;
RA Stroehlein A.J., Korhonen P.K., Chong T.M., Lim Y.L., Chan K.G.,
RA Webster B., Rollinson D., Brindley P.J., Gasser R.B., Young N.D.;
RT "High-quality Schistosoma haematobium genome achieved by single-molecule
RT and long-range sequencing.";
RL Gigascience 8:0-0(2019).
RN [3] {ECO:0000313|EMBL:KAH9596657.1}
RP NUCLEOTIDE SEQUENCE.
RA Stroehlein A.J.;
RT "Chromosome-level genome assembly for S. haematobium.";
RL Submitted (JUN-2021) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:KAH9596657.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=35167626;
RA Stroehlein A.J., Korhonen P.K., Lee V.V., Ralph S.A., Mentink-Kane M.,
RA You H., McManus D.P., Tchuente L.T., Stothard J.R., Kaur P., Dudchenko O.,
RA Aiden E.L., Yang B., Yang H., Emery A.M., Webster B.L., Brindley P.J.,
RA Rollinson D., Chang B.C.H., Gasser R.B., Young N.D.;
RT "Chromosome-level genome of Schistosoma haematobium underpins genome-wide
RT explorations of molecular variation.";
RL PLoS Pathog. 18:0-0(2022).
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DR EMBL; AMPZ02000062; KAF1338798.1; -; Genomic_DNA.
DR EMBL; AMPZ03000001; KAH9596657.1; -; Genomic_DNA.
DR EMBL; KL250502; KGB32421.1; -; Genomic_DNA.
DR RefSeq; XP_012792184.1; XM_012936730.1.
DR AlphaFoldDB; A0A095AEZ3; -.
DR STRING; 6185.A0A095AEZ3; -.
DR EnsemblMetazoa; XM_012936730.2; XP_012792184.1; MS3_0015837.
DR GeneID; 24588357; -.
DR KEGG; shx:MS3_00002266; -.
DR CTD; 24588357; -.
DR OrthoDB; 5548910at2759; -.
DR Proteomes; UP000471633; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00048; DSRM_SF; 1.
DR CDD; cd19857; DSRM_STAU_rpt1; 1.
DR Gene3D; 3.30.160.20; -; 3.
DR InterPro; IPR014720; dsRBD_dom.
DR PANTHER; PTHR46054; MATERNAL EFFECT PROTEIN STAUFEN; 1.
DR PANTHER; PTHR46054:SF3; MATERNAL EFFECT PROTEIN STAUFEN; 1.
DR Pfam; PF00035; dsrm; 1.
DR SMART; SM00358; DSRM; 4.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 3.
DR PROSITE; PS50137; DS_RBD; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000471633};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00266}.
FT DOMAIN 12..84
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 338..415
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 517..536
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 521..536
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 769 AA; 87133 MW; 03BAD95D7D7E52D9 CRC64;
MSFDSETFIN ISPVFILNKQ AHLLKTDLSW TCEDSGPFHN KVFRVSVIVN HHNLKSSEIY
YGVGSSVKEA RRMAAESALQ TCILFKYNAS SSIGALRTGG PFTTPRNADP FIILINSDPT
SLAPKVQLRQ LLNLLGSKVR FVHSMGDANN SLRPIMYRAT AEIVGRQYVG NSTTKSGAEQ
ESCLSALMAL RRSLLSYIKT QKLRKKEQHD QDNMYINRCI HPKSSVWRLR ILAGLHFIQP
LFKIQKLTNC EPNKFTCICL LDGWKYTENR SISAKKAQNT AAQSMLNNMN KIENKCSTVP
FYDKQYDVTS KYVHKQNHKP CKIKLQFNQH RASDESIHPV CRLECYSIVN NLDKVKYTLL
NDQLPSGEHA SLAPGRPPFI YQIEFSNMCI QGPEANNKRL AKRLAAELLL TKLGLSSEKS
SNVKSVLRSK VIESLDSNIH AIKSVSENLS CGLVPETVSN VHKSLSPVEK SDDQSQDTIS
NEEHHVNFSC TSDILIFDEE LVDPVLLSKR TSRPLKRKDI QSRTISSGSI PRSHSSINLS
VNETNNLLQN YSPTSTDIPL INSVSERNRN NLDVFSKTIG YWIDSKKSKP NQKSYARSHS
EVDFTEGSHW YRKFDGIYDN TSLDIITDCT LSKTNIRLQL LARVAEYCLQ EHGPNNSIHK
MNEYHTSQVT SLTDQLVFLC RRLLVPCHFI EYPPKLNIVC KSEKEFNTKY YYEYTVILFV
GINPMKENSI INNSINSNGY ITVKATDLTR NSARHKAAQS VIKRLTKLI
//
