ID   A0A096LVV9_POEFO        Unreviewed;       609 AA.
AC   A0A096LVV9;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   RecName: Full=RING-type domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Poecilia formosa (Amazon molly) (Limia formosa).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000023300.1, ECO:0000313|Proteomes:UP000028760};
RN   [1] {ECO:0000313|Proteomes:UP000028760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA   Schartl M., Warren W.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPFOP00000023300.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   EMBL; AYCK01025698; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01025699; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A096LVV9; -.
DR   STRING; 48698.ENSPFOP00000023300; -.
DR   Ensembl; ENSPFOT00000022694.1; ENSPFOP00000023300.1; ENSPFOG00000023222.1.
DR   eggNOG; ENOG502SBIG; Eukaryota.
DR   GeneTree; ENSGT01100000263487; -.
DR   Proteomes; UP000028760; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR027370; Znf-RING_euk.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   Pfam; PF13445; zf-RING_UBOX; 1.
DR   SMART; SM01288; FISNA; 1.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS50837; NACHT; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          55..97
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   DOMAIN          210..344
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   REGION          15..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        19..41
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   609 AA;  69207 MW;  69B99E6B3373C3FE CRC64;
     MEDLDLKKER AELLGSISPS MRSDWSQDVP LNFSNKPGPS NRKSSVDEEE KPSCCPLCQE
     VLINPVSTSC GHWFCRQCIS YDWDQCAPFG PSSCPQCGKR PRTGTELLTA NQSSCAPADV
     GLQEVLKEHK ISLRSRCECV TEGSDETGSR THLNRIYTDL FITEGQSEDV DTQHEVKQLE
     RVSKIQNLHD SPIRCHDIFK TFRDQHGVIR VVLTIGIAGV GKTFSVQKFT LDWAEGLENQ
     DVSVVVQLSF RELNLIRGEQ HSLLSLLHVF HPTFQKLPAE QLAKCKLLFI FDGLDENRLS
     LDFNNSQLVS DVTQKSSVNV LLTNLIKGNL LPSALIWITT RPAAANQIPP SCVSRVTEVR
     GFTDTQKEEY FRKRFSDEEL SNRIISHIKK SKSLHIMCGI PVFCWITATV LENMLASEQR
     GELPKTMTDM YSHFLLVQTK RKKKKYHGGH EISPQKLMKS DREVLLKLGR LAFEHLEKGN
     IMFYQEDLEQ CGLDVTEASV YSGVCTEIFK RESVIFQKSV YCFVHLSIQE FLAAVYMLHC
     FTSRRSEVIK RFLGQQYGET SLDDFLKKVT KKSLSSKNGH LDLFVRFLHG LTVESNQRLL
     EDLLGQTEN
//