ID   A0A096LXG6_POEFO        Unreviewed;       995 AA.
AC   A0A096LXG6;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=NACHT, LRR and PYD domains-containing protein 3-like {ECO:0000313|Ensembl:ENSPFOP00000023857.1};
OS   Poecilia formosa (Amazon molly) (Limia formosa).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000023857.1, ECO:0000313|Proteomes:UP000028760};
RN   [1] {ECO:0000313|Proteomes:UP000028760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA   Schartl M., Warren W.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPFOP00000023857.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   EMBL; AYCK01000737; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01000738; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01000739; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A096LXG6; -.
DR   Ensembl; ENSPFOT00000029641.1; ENSPFOP00000023857.1; ENSPFOG00000015408.2.
DR   GeneTree; ENSGT01070000253760; -.
DR   Proteomes; UP000028760; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR   CDD; cd00116; LRR_RI; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR018957; Znf_C3HC4_RING-type.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF13516; LRR_6; 4.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   Pfam; PF00097; zf-C3HC4; 1.
DR   SMART; SM01288; FISNA; 1.
DR   SMART; SM00368; LRR_RI; 11.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS51450; LRR; 2.
DR   PROSITE; PS50837; NACHT; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          8..35
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   DOMAIN          147..281
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   995 AA;  111863 MW;  30B81D9FFA2FD701 CRC64;
     MDPVSTRCGH LFCGQCIRSY LDQSATSEHP SCPECGKRSR TGPGLLTVNQ SSLAADVVLQ
     EVLEEHKISL RRRCVSVTEG SDKTESRTLF NKIYTDLYIT EGQGEEINTQ HEVKQLERAS
     KIQDLRYSPI RCHDIFKAFP ARQVTIRVVM TSGVAGVGKT FSVQKFTLDW AESLENQDVS
     VVVPVSFREL NLIRDEQHSL LSLLHVFHPT LQKLTAEQLA ICKLLFIFDG LDESRLSLDF
     GSRQLVSDVT QKSSVNILLT NLIKGDLLPS ALIWITSRPA AANQIPASCV SRVTEVRGFT
     DTQKEEYFRR RFSDEELSSR IISHIQTCRS LHIMCGIPVF CWITATVLEN MLSSEQRGEL
     PKTMTDMYSH FLLVQTKMKK NKYHGGHETS PQELMEADRE VLLKLGRLAF EHLEKGNIMF
     YQEDLEQCGL DVTEASLYSG VCTEIFKRES VIFQKPVYCF VHLTIQEFLA AVYMFHCFTT
     RNTEVIKRFL GQEYRETSLE GFMKKVMEKS LLTKNGHLDL FVRFLHGLTV ESNQRLLGGL
     LGQTENSSET TKRIITNLKE MNTDDISPDR SINLFYCLME IKDLSFFQEI QQLLKSGKEL
     SEIQCSALAF MLLMSEEVLD ELDLKKYNTS EGGRRRLVPA VNNCKKARLG GCELSQAECE
     VLASALKSNP HLTELEISNF TGLEDSGMKH LHEILESSVS KVKMLRLVSC RLSEISCASM
     ASALKSNPSL TELNLCKINL EDAGVKELCG FLQSPDCKIQ QLKLIYCRLS EISCSSLASA
     LKSNQHLTEL DLSNNDLKDS GVKELCGFLQ APNCKLQQLK LECCSLSKIS CDYLISALKS
     NPSHMTELFM SNNNLEDAGV QELCGFLQTP DCKIKTLGLQ RCSLSKISCD YLASVLKSNP
     SNVTELDLSR NDLEDAGVKE LCGFLQTLNC KVKTLRLTTC SLSKISCDYL ASALKFNPSH
     LTELNLSGNK LKESDVQQLK HITEQIPSLN YTTFK
//