ID   A0A096M116_POEFO        Unreviewed;       635 AA.
AC   A0A096M116;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 45.
DE   SubName: Full=Beta-galactosidase-like {ECO:0000313|Ensembl:ENSPFOP00000025107.1};
OS   Poecilia formosa (Amazon molly) (Limia formosa).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000025107.1, ECO:0000313|Proteomes:UP000028760};
RN   [1] {ECO:0000313|Proteomes:UP000028760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA   Schartl M., Warren W.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPFOP00000025107.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC       {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}.
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DR   EMBL; AYCK01013440; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A096M116; -.
DR   Ensembl; ENSPFOT00000022192.1; ENSPFOP00000025107.1; ENSPFOG00000006508.2.
DR   GeneTree; ENSGT00950000182942; -.
DR   OMA; TNKEMIC; -.
DR   Proteomes; UP000028760; Unassembled WGS sequence.
DR   GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR026283; B-gal_1-like.
DR   InterPro; IPR048912; BetaGal1-like_ABD1.
DR   InterPro; IPR048913; BetaGal_gal-bd.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR   InterPro; IPR001944; Glycoside_Hdrlase_35.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR   PANTHER; PTHR23421:SF50; BETA-GALACTOSIDASE-1-LIKE PROTEIN; 1.
DR   Pfam; PF21317; BetaGal_ABD_1; 1.
DR   Pfam; PF21467; BetaGal_gal-bd; 1.
DR   Pfam; PF01301; Glyco_hydro_35; 1.
DR   PIRSF; PIRSF006336; B-gal; 1.
DR   PRINTS; PR00742; GLHYDRLASE35.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           28..635
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5001919761"
FT   DOMAIN          37..355
FT                   /note="Glycoside hydrolase 35 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01301"
FT   DOMAIN          402..514
FT                   /note="Beta-galactosidase 1-like first all-beta"
FT                   /evidence="ECO:0000259|Pfam:PF21317"
FT   DOMAIN          543..600
FT                   /note="Beta-galactosidase galactose-binding"
FT                   /evidence="ECO:0000259|Pfam:PF21467"
FT   REGION          524..545
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        185
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT   ACT_SITE        265
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
SQ   SEQUENCE   635 AA;  71292 MW;  E9F776E0052EDCA3 CRC64;
     MAAASFLFAV CMALSTLSGS LVTGTRSFSI DYKNHCFLKD GKPFQYISGS IHYSRIPQYY
     WKDRLVKMYM TGLNAVQFYN VPWNFHEPVQ GVHNFTGDRD LEHFLNLANQ TGLLVILRPG
     PYICAEWEMG GLPAWLLQKP NIILRSADTD YLEAVSSWLA VLLPKIKPWL YINGGNIITV
     QVENEYGSYF ACDYNYMRHL RTLFRFFLGE DVVLFTTDGN TDKEMTCGSL DGLYATVDFG
     TDTNITVAFK RQRRFEPQGP LVNSEFYTGW LDHWGDQHAM VGAQKVSRVL EEMLTMGASV
     NMYMFEGGTN FGYWNGADHD SRFRSVVTSY DYDAPLTEAG DPTEKLLAIR DVIKQFRDIP
     AGPMPPATPK FAYGFVTLEK IGNISSLLDT ISPLGPVQSK YPLTFEEMKQ YYGYMLYRTT
     LPHDLTEPTP LISPLNGVHD RAYVSVNGVF QGLLQRDTVL VMNVTGKQGD TLDILVENMG
     RVNFGSKIND YKGLVSNLIL GKDVLTDWKI YPLDIDGAIS RGWPHSNSGK SVTSPRREPS
     AGPTFYTGTL QPNGLAWDTF LKLIEWTKGQ VWINGVNLGR YWPGRGPQQT LYVPGPLLST
     SLPNNITLLE LEGAPAHLRI VFMDRPQLNA TAGKS
//