ID A0A096M2U0_POEFO Unreviewed; 305 AA.
AC A0A096M2U0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase {ECO:0000256|ARBA:ARBA00040603};
DE EC=1.1.1.179 {ECO:0000256|ARBA:ARBA00038984};
DE EC=1.3.1.20 {ECO:0000256|ARBA:ARBA00038853};
DE AltName: Full=D-xylose 1-dehydrogenase {ECO:0000256|ARBA:ARBA00043025};
DE AltName: Full=D-xylose-NADP dehydrogenase {ECO:0000256|ARBA:ARBA00042988};
DE AltName: Full=Dimeric dihydrodiol dehydrogenase {ECO:0000256|ARBA:ARBA00042926};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000025731.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000025731.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(1R,2R)-1,2-dihydrobenzene-1,2-diol + NADP(+) = catechol +
CC H(+) + NADPH; Xref=Rhea:RHEA:16729, ChEBI:CHEBI:10702,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:18135, ChEBI:CHEBI:57783,
CC ChEBI:CHEBI:58349; EC=1.3.1.20;
CC Evidence={ECO:0000256|ARBA:ARBA00036133};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-xylose + NADP(+) = D-xylono-1,5-lactone + H(+) + NADPH;
CC Xref=Rhea:RHEA:22000, ChEBI:CHEBI:15378, ChEBI:CHEBI:15867,
CC ChEBI:CHEBI:53455, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349;
CC EC=1.1.1.179; Evidence={ECO:0000256|ARBA:ARBA00036678};
CC -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family.
CC {ECO:0000256|ARBA:ARBA00010928}.
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DR EMBL; AYCK01004751; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A096M2U0; -.
DR STRING; 48698.ENSPFOP00000025731; -.
DR Ensembl; ENSPFOT00000031863.1; ENSPFOP00000025731.1; ENSPFOG00000022313.1.
DR eggNOG; KOG2741; Eukaryota.
DR GeneTree; ENSGT00390000007946; -.
DR OMA; QLALWVY; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR22604; OXIDOREDUCTASES; 1.
DR PANTHER; PTHR22604:SF105; TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE; 1.
DR Pfam; PF01408; GFO_IDH_MocA; 1.
DR Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT DOMAIN 1..92
FT /note="Gfo/Idh/MocA-like oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01408"
FT DOMAIN 108..244
FT /note="Gfo/Idh/MocA-like oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02894"
SQ SEQUENCE 305 AA; 34439 MW; 9EC03DA04D6F2D99 CRC64;
QVVAVAARKL EDAQEFANKH SISRVYGSYE ELARDPDMDI VHVGVIPPYH LNACKLFINA
KKNVLCEKSL AMNTKELKEI LDSAKKNNVF LMEAVWTRFF QASVEIRNLL AQEYIGEVKM
VRADYSLPLL HMSRSDQKDL SEGALLGLGI YCLQFISMVY KGEKPESIQA RGVCLETGVD
ETVAVILRYS KNRMATFTCS AGVELHSEAI IIGTEGKIQV LSPMWCPTSI IVDRKETEYP
IPERCLSLNF TYSTGKRYEV EEVRQCLLKG LKESPVTPHA YTLLLAEMGD EIRRQVDVVY
SQDCQ
//
