ID A0A096MBR2_POEFO Unreviewed; 373 AA.
AC A0A096MBR2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=Potassium channel voltage dependent KCNQ C-terminal domain-containing protein {ECO:0000259|Pfam:PF03520};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000028853.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000028853.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AYCK01028287; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A096MBR2; -.
DR STRING; 48698.ENSPFOP00000028853; -.
DR Ensembl; ENSPFOT00000026887.1; ENSPFOP00000028853.1; ENSPFOG00000024058.1.
DR eggNOG; KOG1419; Eukaryota.
DR GeneTree; ENSGT00940000165345; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR Gene3D; 6.10.140.1910; -; 1.
DR InterPro; IPR020969; Ankyrin-G_BS.
DR InterPro; IPR003937; K_chnl_volt-dep_KCNQ.
DR InterPro; IPR013821; K_chnl_volt-dep_KCNQ_C.
DR PANTHER; PTHR47735:SF4; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 2; 1.
DR PANTHER; PTHR47735; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4; 1.
DR Pfam; PF16642; KCNQ2_u3; 1.
DR Pfam; PF03520; KCNQ_channel; 1.
DR Pfam; PF11956; KCNQC3-Ank-G_bd; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692}.
FT DOMAIN 6..147
FT /note="Potassium channel voltage dependent KCNQ C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03520"
FT REGION 95..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 155..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 189..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 314..373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..110
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 189..237
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 256..280
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 373 AA; 40613 MW; 0234E282DCFA8CB6 CRC64;
TSAFVSDASL PGEDMADDNK SCHCEFVPQD LTPGLKVTIR AICIMRFMVS KRKFKESLRP
YDVMDVIEQY SAGHLDMLAR IKNLQARVDQ IVGRGTPIAD KDRPKSGGEE IPEDPSMMGR
LGKVEKQVLS MERKLDFLVN IYIQRMGIPQ AETDAYFGSK EPDPAPPYHS PVEVLPGDHM
ERTRFVTKMV RSSSSTGHRN YAAPTCPPST SWQPISSQLH QQAPPPPQRS HGNTPSPVGD
ASLVRLPPPP AGERHGGNRP SRHGGGERAG TERNGDEAKL DSDTSVSIPS VDHEELERSF
SGFSISQSRE NLDFLNNGFY PSAGPGEQPA GGSGGGSVRR AARRPYIAQG ESDSDSELCA
PSPHSDRAWT GTK
//
