ID A0A096NQE1_PAPAN Unreviewed; 797 AA.
AC A0A096NQE1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Interphotoreceptor matrix proteoglycan 1 {ECO:0000256|ARBA:ARBA00040753};
DE AltName: Full=Sialoprotein associated with cones and rods {ECO:0000256|ARBA:ARBA00042018};
GN Name=IMPG1 {ECO:0000313|Ensembl:ENSPANP00000015235.3};
OS Papio anubis (Olive baboon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Papio.
OX NCBI_TaxID=9555 {ECO:0000313|Ensembl:ENSPANP00000015235.3, ECO:0000313|Proteomes:UP000028761};
RN [1] {ECO:0000313|Ensembl:ENSPANP00000015235.3, ECO:0000313|Proteomes:UP000028761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A., Aqrawi P.A.,
RA Arias F.A., Attaway T.A., Awwad R.A., Babu C.B., Bandaranaike D.B.,
RA Battles P.B., Bell A.B., Beltran B.B., Berhane-Mersha D.B., Bess C.B.,
RA Bickham C.B., Bolden T.B., Carter K.C., Chau D.C., Chavez A.C.,
RA Clerc-Blankenburg K.C., Coyle M.C., Dao M.D., Davila M.L.D.,
RA Davy-Carroll L.D., Denson S.D., Dinh H.D., Fernandez S.F., Fernando P.F.,
RA Forbes L.F., Francis C.F., Francisco L.F., Fu Q.F., Garcia-Iii R.G.,
RA Garrett T.G., Gross S.G., Gubbala S.G., Hirani K.H., Hogues M.H.,
RA Hollins B.H., Jackson L.J., Javaid M.J., Jhangiani S.J., Johnson A.J.,
RA Johnson B.J., Jones J.J., Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K.,
RA Kovar C.K., Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L.,
RA Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L.,
RA Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M.,
RA Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N.,
RA Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O.,
RA Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P., Perez Y.P.,
RA Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q., Rouhana J.R., Ruiz M.R.,
RA Ruiz S.-J.R., Saada N.S., Santibanez J.S., Scheel M.S., Schneider B.S.,
RA Simmons D.S., Sisson I.S., Tang L.-Y.T., Thornton R.T., Tisius J.T.,
RA Toledanes G.T., Trejos Z.T., Usmani K.U., Varghese R.V., Vattathil S.V.,
RA Vee V.V., Walker D.W., Weissenberger G.W., White C.W., Williams A.W.,
RA Woodworth J.W., Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N.,
RA Nazareth L.N., Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.;
RT "Whole Genome Assembly of Papio anubis.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPANP00000015235.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium, photoreceptor outer
CC segment {ECO:0000256|ARBA:ARBA00004504}. Photoreceptor inner segment
CC {ECO:0000256|ARBA:ARBA00004437}. Secreted, extracellular space,
CC extracellular matrix, interphotoreceptor matrix
CC {ECO:0000256|ARBA:ARBA00004593}.
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DR AlphaFoldDB; A0A096NQE1; -.
DR STRING; 9555.ENSPANP00000015235; -.
DR Ensembl; ENSPANT00000027213.3; ENSPANP00000015235.3; ENSPANG00000019906.3.
DR eggNOG; ENOG502QTXX; Eukaryota.
DR GeneTree; ENSGT00530000063503; -.
DR HOGENOM; CLU_005111_1_0_1; -.
DR OMA; SECVMNE; -.
DR OrthoDB; 4244504at2759; -.
DR Proteomes; UP000028761; Chromosome 6.
DR Bgee; ENSPANG00000019906; Expressed in retina and 5 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0033165; C:interphotoreceptor matrix; IEA:UniProtKB-SubCell.
DR GO; GO:0001917; C:photoreceptor inner segment; IEA:UniProtKB-SubCell.
DR GO; GO:0001750; C:photoreceptor outer segment; IEA:UniProtKB-SubCell.
DR GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR GO; GO:0005540; F:hyaluronic acid binding; IEA:UniProtKB-KW.
DR GO; GO:0007601; P:visual perception; IEA:InterPro.
DR Gene3D; 3.30.70.960; SEA domain; 2.
DR InterPro; IPR039861; IMPG.
DR InterPro; IPR000082; SEA_dom.
DR InterPro; IPR036364; SEA_dom_sf.
DR PANTHER; PTHR12199; INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN; 1.
DR PANTHER; PTHR12199:SF3; INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN 1; 1.
DR Pfam; PF01390; SEA; 2.
DR SMART; SM00200; SEA; 2.
DR SUPFAM; SSF82671; SEA domain; 2.
DR PROSITE; PS50024; SEA; 2.
PE 4: Predicted;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00022981};
KW Heparin-binding {ECO:0000256|ARBA:ARBA00022674};
KW Hyaluronic acid {ECO:0000256|ARBA:ARBA00023290};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000028761};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Sialic acid {ECO:0000256|ARBA:ARBA00022981};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..797
FT /note="Interphotoreceptor matrix proteoglycan 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5035179083"
FT DOMAIN 232..354
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
FT DOMAIN 571..684
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
SQ SEQUENCE 797 AA; 89524 MW; FE790CA4C4D0ED00 CRC64;
MYLETRRAIF VFWIFLQVQG TEDISINIYH SETKDIDNPP RNETTESTEK MYKMSTMRRI
FDLAKHRTKR SAFFPTGVKV CPQESMKQIL ASLQAYYRLR VCQEAVWEAY RIFLDRIPDT
GEYQEWVSFC QQETFCLFDI GQNFSNSQEH LDLLQQRIKQ RSFPERKDEV STEKTLGEPS
ETIVVSTDVA SVSLGPSPVT PDDTLLNEIL DNVLNDTKMP TTERETELAV SEEQRVELSI
SLINQRFKAE LADSQSPYYQ ELAGKSQLQM QKIFKKLPGF KKIHVLGFRP KKEKDGSSST
EMQLTAIFKR HSAEAKSPAS DLPSFDSNKI ESEEVYHGTM EEDKQPEIYL TATDLKRLIS
KALEEEQSLD VGTIQFTDEI TGSLPAFGPD TQSELPTTFA DITEDATLSP ELPLVEPQLE
IVDRAEHGLP DISWSPPAMA STSLSETPPF FTASSIISLT DQGTTDIMAI DQTVLVPALT
IPTSDYSAIS QLTLGISHPP ASSDDSRSSA GGEDIVRDLD EMDLSETPAP SEVAELSEYV
SVPDHFLEDT TPVSALQYIT TSSMTIAPKG RELVVFFSLR VANMAFSNDL FNKSSLEYRA
LEQQFTQLLV PYLRSNLTGF KQLEILNFRN GSVIVNSKMK FAKSVPYNLT KAVHGVLEDF
RSAAAQQLHM EIDSYSLNIE PADQADPCKF LACGEFAQCV KNEWTEEAEC RCKPGYESQA
GLDGLEPGLC GPGTKECEVL QGKGAPCRLP DHSENQAYKT SVKKFQNQQN NKVISKRNSE
LLTIEYEEFN HQDWEGN
//
