ID A0A097R3Z9_HAFAL Unreviewed; 216 AA.
AC A0A097R3Z9;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE RecName: Full=Transcriptional regulatory protein RcsB {ECO:0000256|HAMAP-Rule:MF_00981};
GN Name=rcsB {ECO:0000256|HAMAP-Rule:MF_00981};
GN ORFNames=AT03_14325 {ECO:0000313|EMBL:AIU73445.1};
OS Hafnia alvei FB1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Hafniaceae; Hafnia.
OX NCBI_TaxID=1453496 {ECO:0000313|EMBL:AIU73445.1, ECO:0000313|Proteomes:UP000029986};
RN [1] {ECO:0000313|EMBL:AIU73445.1, ECO:0000313|Proteomes:UP000029986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FB1 {ECO:0000313|EMBL:AIU73445.1,
RC ECO:0000313|Proteomes:UP000029986};
RX PubMed=25075225; DOI=10.1186/1757-4749-6-29;
RA Tan J.Y., Yin W.F., Chan K.G.;
RT "Gene clusters of Hafnia alvei strain FB1 important in survival and
RT pathogenesis: a draft genome perspective.";
RL Gut Pathog. 6:29-29(2014).
CC -!- FUNCTION: Component of the Rcs signaling system, which controls
CC transcription of numerous genes. RcsB is the response regulator that
CC binds to regulatory DNA regions. {ECO:0000256|HAMAP-Rule:MF_00981}.
CC -!- SUBUNIT: Interacts with RcsD. {ECO:0000256|HAMAP-Rule:MF_00981}.
CC -!- PTM: Phosphorylated and activated by RcsD. {ECO:0000256|HAMAP-
CC Rule:MF_00981}.
CC -!- SIMILARITY: Belongs to the RcsB family. {ECO:0000256|HAMAP-
CC Rule:MF_00981}.
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DR EMBL; CP009706; AIU73445.1; -; Genomic_DNA.
DR RefSeq; WP_025798039.1; NZ_CP009706.1.
DR AlphaFoldDB; A0A097R3Z9; -.
DR GeneID; 78451594; -.
DR KEGG; hav:AT03_14325; -.
DR PATRIC; fig|1453496.5.peg.2923; -.
DR eggNOG; COG2197; Bacteria.
DR HOGENOM; CLU_000445_90_1_6; -.
DR OrthoDB; 4313922at2; -.
DR Proteomes; UP000029986; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR CDD; cd06170; LuxR_C_like; 1.
DR CDD; cd17535; REC_NarL-like; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR HAMAP; MF_00981; RcsB; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR030864; RcsB.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR45566; HTH-TYPE TRANSCRIPTIONAL REGULATOR YHJB-RELATED; 1.
DR PANTHER; PTHR45566:SF2; NARL SUBFAMILY; 1.
DR Pfam; PF00196; GerE; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00421; HTH_LUXR; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR PROSITE; PS00622; HTH_LUXR_1; 1.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00981};
KW Phosphoprotein {ECO:0000256|HAMAP-Rule:MF_00981, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000029986};
KW Transcription {ECO:0000256|HAMAP-Rule:MF_00981};
KW Transcription regulation {ECO:0000256|HAMAP-Rule:MF_00981};
KW Two-component regulatory system {ECO:0000256|HAMAP-Rule:MF_00981}.
FT DOMAIN 5..124
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 144..209
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50043"
FT MOD_RES 56
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00981,
FT ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 216 AA; 23688 MW; A83A477B286AE244 CRC64;
MNNLNVIIAD DHPIVLFGIR KSLEQIEWVN VVGEFEDSTA LINSLSKLDA NVLITDLSMP
GDKYGDGITL IKYIKRHYPH LSIIVLTMNN NPAILSAVLE LDIEGIVLKQ GAPADLPKAL
AALQKGKKFT PESVSKLLEK ISASGYGDKR LSPKESEVLR LFAEGFLVTE IAKKLNRSIK
TISSQKKSAM LKLGVDNDIA LLNYLSSVNI MSVDKD
//
