ID A0A098VWG2_9MICR Unreviewed; 658 AA.
AC A0A098VWG2;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 22-FEB-2023, entry version 31.
DE RecName: Full=Translocation protein SEC62 {ECO:0000256|ARBA:ARBA00021257};
GN ORFNames=DI09_102p80 {ECO:0000313|EMBL:KGG53224.1};
OS Mitosporidium daphniae.
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Mitosporidium.
OX NCBI_TaxID=1485682 {ECO:0000313|EMBL:KGG53224.1, ECO:0000313|Proteomes:UP000029725};
RN [1] {ECO:0000313|EMBL:KGG53224.1, ECO:0000313|Proteomes:UP000029725}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UGP3 {ECO:0000313|EMBL:KGG53224.1,
RC ECO:0000313|Proteomes:UP000029725};
RC TISSUE=Spores {ECO:0000313|EMBL:KGG53224.1};
RA Haag K.L., James T.Y., Larsson R., Schaer T.M., Refardt D., Pombert J.-F.,
RA Ebert D.;
RT "A new species of microsporidia sheds light on the evolution of extreme
RT parasitism.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SEC62 family.
CC {ECO:0000256|ARBA:ARBA00010604}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGG53224.1}.
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DR EMBL; JMKJ01000003; KGG53224.1; -; Genomic_DNA.
DR RefSeq; XP_013239660.1; XM_013384206.1.
DR AlphaFoldDB; A0A098VWG2; -.
DR GeneID; 25257896; -.
DR VEuPathDB; MicrosporidiaDB:DI09_102p80; -.
DR HOGENOM; CLU_416825_0_0_1; -.
DR OrthoDB; 51571at2759; -.
DR Proteomes; UP000029725; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046907; P:intracellular transport; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000156; Ran_bind_dom.
DR InterPro; IPR004728; Sec62.
DR PANTHER; PTHR12443; TRANSLOCATION PROTEIN SEC62; 1.
DR PANTHER; PTHR12443:SF9; TRANSLOCATION PROTEIN SEC62; 1.
DR Pfam; PF00638; Ran_BP1; 1.
DR Pfam; PF03839; Sec62; 1.
DR SMART; SM00160; RanBD; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50196; RANBD1; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000029725};
KW Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 161..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 518..657
FT /note="RanBD1"
FT /evidence="ECO:0000259|PROSITE:PS50196"
FT REGION 259..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 496..521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..282
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 658 AA; 72861 MW; 13A83FBF4798E73B CRC64;
MAVVAKKRSS DINSLSSKQL GQVADFLKSS VPIYDAISIE RRVEIFSGRE AVSILLESSS
SGNKKKPFPL DFAITSPDHA KQLLLMLLKN GYFIKAMVNG TKEIPLTPMQ QAMIRAETIS
GNQSPNVQLP KPEVIYLVSP DPSVSWSEDT KFIWIYEGSK LFSTMLSFGI LILLFFGIMY
PLWPYQLRLG AWYLTMVCIA LVGLLLLVSV IRLVLYLLCL IAGLPGFWIF PNLYEDCGFF
ESFVPLASAY QITQLAPTEE DVRPCENSGS EDEQAEEEEP RRFLDNSFKN TAEKISFKPF
AKGMVQTSQT SKPDLKDAPT AFDAPLHIHG LNKCFLEHIE KTFKVNPTGD LSGTFDTYRN
HLQEIMSKSQ NGNLDSKSPA VLQTTDFNEN INMSVQREGP ATKNDSKSLL SFNTLVDKPA
SNFSFLSPAS ASTVSSEFTS EKPPFSFALN ASEPAQKPFS FMKPSSEAKS LFSLPSSTSA
SGSIFSFLTA DKPDFSSTEQ AKNAELEKEE TGHGEEEEDE PVVIEEVDPC VKGPGEESDT
VIFALKCKVY VMALSQSDKT WQDLGVASLR INETSCPDSA PKQRIIARAQ GSTSKLLLNS
YASGISLMPL KPSEKSVSFI SLNPEEKLTC YLIRAKTEQS LHELYSHLEK YSRKELAT
//
