ID A0A099D0R7_9ACTN Unreviewed; 331 AA.
AC A0A099D0R7;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Aldo/keto reductase {ECO:0000313|EMBL:ASU79651.1};
GN ORFNames=CDG81_16805 {ECO:0000313|EMBL:ASU79651.1}, IL38_23310
GN {ECO:0000313|EMBL:KGI79422.1};
OS Actinopolyspora erythraea.
OC Bacteria; Actinomycetota; Actinomycetes; Actinopolysporales;
OC Actinopolysporaceae; Actinopolyspora.
OX NCBI_TaxID=414996 {ECO:0000313|EMBL:ASU79651.1, ECO:0000313|Proteomes:UP000215043};
RN [1] {ECO:0000313|EMBL:KGI79422.1, ECO:0000313|Proteomes:UP000029737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM90600 {ECO:0000313|EMBL:KGI79422.1,
RC ECO:0000313|Proteomes:UP000029737};
RX PubMed=25250723;
RA Chen D., Feng J., Huang L., Zhang Q., Wu J., Zhu X., Duan Y., Xu Z.;
RT "Identification and Characterization of a New Erythromycin Biosynthetic
RT Gene Cluster in Actinopolyspora erythraea YIM90600, a Novel Erythronolide-
RT Producing Halophilic Actinomycete Isolated from Salt Field.";
RL PLoS ONE 9:E108129-E108129(2014).
RN [2] {ECO:0000313|EMBL:ASU79651.1, ECO:0000313|Proteomes:UP000215043}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM 90600 {ECO:0000313|EMBL:ASU79651.1,
RC ECO:0000313|Proteomes:UP000215043};
RA Yin M., Tang S.;
RT "The complete genome sequence of moderately halophilic actinomycete
RT Actinopolyspora erythraea YIM 90600, the producer of novel erythromycin,
RT novel actinopolysporins A-C and tubercidin.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP022752; ASU79651.1; -; Genomic_DNA.
DR EMBL; JPMV01000045; KGI79422.1; -; Genomic_DNA.
DR RefSeq; WP_043578273.1; NZ_KN214180.1.
DR AlphaFoldDB; A0A099D0R7; -.
DR KEGG; aey:CDG81_16805; -.
DR eggNOG; COG0667; Bacteria.
DR HOGENOM; CLU_023205_2_1_11; -.
DR OrthoDB; 3664926at2; -.
DR Proteomes; UP000029737; Unassembled WGS sequence.
DR Proteomes; UP000215043; Chromosome.
DR CDD; cd19076; AKR_AKR13A_13D; 1.
DR Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR InterPro; IPR023210; NADP_OxRdtase_dom.
DR InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR PANTHER; PTHR43625; AFLATOXIN B1 ALDEHYDE REDUCTASE; 1.
DR PANTHER; PTHR43625:SF77; ALDO-KETO REDUCTASE; 1.
DR Pfam; PF00248; Aldo_ket_red; 1.
DR SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
PE 4: Predicted;
FT DOMAIN 17..310
FT /note="NADP-dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00248"
SQ SEQUENCE 331 AA; 36653 MW; DB31777BD6E365B3 CRC64;
MRQRALGSQG LRVSEQGLGC MGMTFGYSGW DDEESAATIR RALELGVNFL DTADIYGPWS
NERLLGGTLA GHRDEVVLAT KFGGSEINEN GELTGRTNGR PEYLRAAVDG SLRRLGVDHI
DLYYQHRVDP DVPIAETWGA MSELVRQGKV RYLGISEAAP ETIRKAHATH PVSAVQTEYS
LFSRDPEDNG VLDTCRELGI GFVAYSPLGR GFLSGTIRSF EDLPEDDWRR TAPRFRGENF
RRNLDVVDRV HELAHRKGVS ASQLALAWVM SRGEDVVAIP GTKKRRYLEE NVGAVDVTLT
PEDLEAIERV APHGVVSGER YDEDGMSKVH L
//
