ID A0A099DAH3_9ACTN Unreviewed; 218 AA.
AC A0A099DAH3;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Phosphate-specific transport system accessory protein PhoU {ECO:0000256|PIRNR:PIRNR003107};
GN Name=phoU {ECO:0000313|EMBL:ASU80435.1};
GN ORFNames=CDG81_21605 {ECO:0000313|EMBL:ASU80435.1}, IL38_03270
GN {ECO:0000313|EMBL:KGI82896.1};
OS Actinopolyspora erythraea.
OC Bacteria; Actinomycetota; Actinomycetes; Actinopolysporales;
OC Actinopolysporaceae; Actinopolyspora.
OX NCBI_TaxID=414996 {ECO:0000313|EMBL:ASU80435.1, ECO:0000313|Proteomes:UP000215043};
RN [1] {ECO:0000313|EMBL:KGI82896.1, ECO:0000313|Proteomes:UP000029737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM90600 {ECO:0000313|EMBL:KGI82896.1,
RC ECO:0000313|Proteomes:UP000029737};
RX PubMed=25250723;
RA Chen D., Feng J., Huang L., Zhang Q., Wu J., Zhu X., Duan Y., Xu Z.;
RT "Identification and Characterization of a New Erythromycin Biosynthetic
RT Gene Cluster in Actinopolyspora erythraea YIM90600, a Novel Erythronolide-
RT Producing Halophilic Actinomycete Isolated from Salt Field.";
RL PLoS ONE 9:E108129-E108129(2014).
RN [2] {ECO:0000313|EMBL:ASU80435.1, ECO:0000313|Proteomes:UP000215043}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM 90600 {ECO:0000313|EMBL:ASU80435.1,
RC ECO:0000313|Proteomes:UP000215043};
RA Yin M., Tang S.;
RT "The complete genome sequence of moderately halophilic actinomycete
RT Actinopolyspora erythraea YIM 90600, the producer of novel erythromycin,
RT novel actinopolysporins A-C and tubercidin.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Plays a role in the regulation of phosphate uptake.
CC {ECO:0000256|PIRNR:PIRNR003107}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|PIRNR:PIRNR003107}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR003107}.
CC -!- SIMILARITY: Belongs to the PhoU family.
CC {ECO:0000256|PIRNR:PIRNR003107}.
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DR EMBL; CP022752; ASU80435.1; -; Genomic_DNA.
DR EMBL; JPMV01000009; KGI82896.1; -; Genomic_DNA.
DR RefSeq; WP_043569982.1; NZ_KN214174.1.
DR AlphaFoldDB; A0A099DAH3; -.
DR KEGG; aey:CDG81_21605; -.
DR eggNOG; COG0704; Bacteria.
DR HOGENOM; CLU_078518_1_0_11; -.
DR OrthoDB; 9814256at2; -.
DR Proteomes; UP000029737; Unassembled WGS sequence.
DR Proteomes; UP000215043; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030643; P:intracellular phosphate ion homeostasis; IEA:InterPro.
DR GO; GO:0045936; P:negative regulation of phosphate metabolic process; IEA:InterPro.
DR GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR028366; P_transport_PhoU.
DR InterPro; IPR038078; PhoU-like_sf.
DR InterPro; IPR026022; PhoU_dom.
DR NCBIfam; TIGR02135; phoU_full; 1.
DR PANTHER; PTHR42930; PHOSPHATE-SPECIFIC TRANSPORT SYSTEM ACCESSORY PROTEIN PHOU; 1.
DR PANTHER; PTHR42930:SF3; PHOSPHATE-SPECIFIC TRANSPORT SYSTEM ACCESSORY PROTEIN PHOU; 1.
DR Pfam; PF01895; PhoU; 2.
DR PIRSF; PIRSF003107; PhoU; 1.
DR SUPFAM; SSF109755; PhoU-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|PIRNR:PIRNR003107};
KW Phosphate transport {ECO:0000256|PIRNR:PIRNR003107};
KW Transport {ECO:0000256|PIRNR:PIRNR003107}.
FT DOMAIN 18..103
FT /note="PhoU"
FT /evidence="ECO:0000259|Pfam:PF01895"
FT DOMAIN 122..204
FT /note="PhoU"
FT /evidence="ECO:0000259|Pfam:PF01895"
SQ SEQUENCE 218 AA; 24208 MW; 16E200B0A55040FF CRC64;
MREVYQEQLD KLADELAAMS TMVGNAMEQA TTALLGADLS LAEQVIDDDM KVDEARARCE
EHAFGLLALQ APVAGDLRTV ISTIHAAESL ERMGDLALHV AKAARRRHPQ PVLPEDVQTY
FSQMGQVAVK LANRLNQILR TQDVQQARDL EVDDDEMDDL HRHLFSVVMG SEWSHGVSAA
VDITLLGRFY ERFADHAVSV ARRIVYVVTG TMPNSDRP
//
