ID A0A099JNP8_9MICO Unreviewed; 493 AA.
AC A0A099JNP8;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=MFS transporter {ECO:0000313|EMBL:KGJ79786.1};
GN ORFNames=GY21_03775 {ECO:0000313|EMBL:KGJ79786.1};
OS Cryobacterium roopkundense.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Cryobacterium.
OX NCBI_TaxID=1001240 {ECO:0000313|EMBL:KGJ79786.1, ECO:0000313|Proteomes:UP000029864};
RN [1] {ECO:0000313|EMBL:KGJ79786.1, ECO:0000313|Proteomes:UP000029864}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RuG17 {ECO:0000313|EMBL:KGJ79786.1,
RC ECO:0000313|Proteomes:UP000029864};
RA Sisinthy S.;
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGJ79786.1}.
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DR EMBL; JPXF01000009; KGJ79786.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A099JNP8; -.
DR STRING; 1001240.GY21_03775; -.
DR eggNOG; COG2252; Bacteria.
DR Proteomes; UP000029864; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029864};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 41..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..457
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 469..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 493 AA; 50879 MW; 1EE0AED829D5F803 CRC64;
MPPESVPPAA APPQASGLKA RFDRYFEVTS RGSTWGREVR GGLVTFVTMA YIVILNPLIL
GGFSADQASV DVEGGWLPAE QVAAVTALTA GVMTILFGVV ARLPYGFAAG LGINSFLAVS
VVGQVTWQEA MGLVVINGLI IVLLASTGMR ELIFNAVPRQ LKIAITVGIG LFIAFIGLVD
SGFVRSSGTA SPPVQLGDAG SIATLPTAVF VVGLIIIGVL LARKVKAALL IGIVATTLIA
IVLEAIFKVG PSFGTNPAGW NLNAPVLPTQ VMSLPDLSLV GQVSFGAFER IGMLAAVMLV
FTLVFTNFFD AMGTMTGLAN EAGLADKNGN FPRLKSALIV EGIGAVAGGA ASASSNTVFI
ESGAGIGEGA RTGFANVITG VLFLAAMFFT PLTQIVPLEV AAAALVIVGA MMVSQIRHID
FAEFSIVLPV FLTIVVMPLT YSIANGIGAG FVSWVLVRSL SGKAKEISPL LWIVAAGFVL
FFVRGPVEAL LGA
//
