ID A0A099P1Y3_PICKU Unreviewed; 488 AA.
AC A0A099P1Y3;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Hexaprenyl pyrophosphate synthase, mitochondrial {ECO:0000313|EMBL:ONH71625.1};
GN ORFNames=BOH78_4394 {ECO:0000313|EMBL:ONH71625.1}, C5L36_0D01990
GN {ECO:0000313|EMBL:AWU77455.1}, JL09_g2487
GN {ECO:0000313|EMBL:KGK38294.1};
OS Pichia kudriavzevii (Yeast) (Issatchenkia orientalis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Pichia.
OX NCBI_TaxID=4909 {ECO:0000313|EMBL:KGK38294.1, ECO:0000313|Proteomes:UP000029867};
RN [1] {ECO:0000313|Proteomes:UP000029867}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SD108 {ECO:0000313|Proteomes:UP000029867};
RX PubMed=25159171; DOI=10.1186/s12934-014-0121-4;
RA Xiao H., Shao Z., Jiang Y., Dole S., Zhao H.;
RT "Exploiting Issatchenkia orientalis SD108 for succinic acid production.";
RL Microb. Cell Fact. 13:121-121(2014).
RN [2] {ECO:0000313|EMBL:KGK38294.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SD108 {ECO:0000313|EMBL:KGK38294.1};
RA Xiao H., Shao Z., Jiang Y., Dole S., Zhao H.;
RT "Exploiting Issatchenkia orientalis SD108 for Succinic Acid Production.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000189274}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=129 {ECO:0000313|Proteomes:UP000189274};
RX PubMed=28385833; DOI=10.1128/genomeA.00064-17;
RA van Rijswijck I.M.H., Derks M.F.L., Abee T., de Ridder D., Smid E.J.;
RT "Genome sequences of Cyberlindnera fabianii 65, Pichia kudriavzevii 129,
RT and Saccharomyces cerevisiae 131 isolated from fermented masau fruits in
RT Zimbabwe.";
RL Genome Announc. 5:E00064-E00064(2017).
RN [4] {ECO:0000313|EMBL:ONH71625.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=129 {ECO:0000313|EMBL:ONH71625.1};
RA Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:AWU77455.1, ECO:0000313|Proteomes:UP000249293}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS573 {ECO:0000313|EMBL:AWU77455.1,
RC ECO:0000313|Proteomes:UP000249293};
RA Douglass A.P., Offei B., Braun-Galleani S., Coughlan A.Y., Martos A.,
RA Ortiz-Merino R.A., Byrne K.P., Wolfe K.H.;
RT "Population genomics shows no distinction between pathogenic Candida krusei
RT and environmental Pichia kudriavzevii: One species, four names.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR EMBL; CP028776; AWU77455.1; -; Genomic_DNA.
DR EMBL; JQFK01000021; KGK38294.1; -; Genomic_DNA.
DR EMBL; MQVM01000031; ONH71625.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A099P1Y3; -.
DR STRING; 4909.A0A099P1Y3; -.
DR VEuPathDB; FungiDB:C5L36_0D01990; -.
DR eggNOG; KOG0776; Eukaryota.
DR HOGENOM; CLU_014015_1_0_1; -.
DR OrthoDB; 25272at2759; -.
DR Proteomes; UP000029867; Unassembled WGS sequence.
DR Proteomes; UP000189274; Unassembled WGS sequence.
DR Proteomes; UP000249293; Chromosome 4.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR GO; GO:1901663; P:quinone biosynthetic process; IEA:UniProt.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001:SF69; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 2.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 2.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000249293};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 488 AA; 54008 MW; D7DE775EF0238490 CRC64;
MLRIAKTVRG RVQISNIKSF NHLLTTRRHG SSFGAAIETA EKMVQPNVSS RFDPFSMVSA
EMGVLAKHIA QLIGSGHPVL NRVTSYYFEA EGKNVRPLIV LLLSKALAAI PEGERTRIHI
DQYDVNTQTE FKGTPKAFSF AGANPLDSIS PLRVLHGINP NIILNPLSRP MLDQDDYEKL
DKVNGILPKQ RRLAEITEMI HTASLLHDDV IDFADSRRGR DSGNVAFSNK MAILAGDFLL
GRASVCLGRL RNSEVVELMS TAIANLVEGE FMQLKNTVLQ PDVKSIENGG EVKRIPDATG
KVPVQVHEYS VNLSEQYKIT HKDNVHAAFE YYLHKTYLKT ASLMSKSSRS TAILAGCDEK
IIENAYQFGR NLGLCFQIVD DMLDYTTTAE LLGKPAGADL KLGLATAPVL YAWEAKPELG
EMIARKFSQP GDVEIAKVAV DETKGVEKTR QLAEKYRDEA LFNLRQLPES DARSALELLT
NSVLTRSK
//
